This year, we have gone beyond just planning experiments. We have troubleshooted each design aspect of our project, presenting multiple alternatives should they fail. This has been done for both our wet lab and hardware components. We have had great fun in doing this and hope you have fun reading this too! Here’s a PDF of the document shown here.
Experimental Design Only
- Falvo E, Arcovito A, Conti G, Cipolla G, Pitea M, Morea V, Damiani V, Sala G, Fracasso G, Ceci P. Engineered Human Nanoferritin Bearing the Drug Genz-644282 for Cancer Therapy. Pharmaceutics. 2020 Oct 20;12(10):992. doi: 10.3390/pharmaceutics12100992. PMID: 33092088; PMCID: PMC7589674.
- Identification of a Minimal Peptide Tag for in Vivo and in Vitro Loading of Encapsulin; Caleb Cassidy-Amstutz, Luke Oltrogge, Catherine C. Going, Antony Lee, Poh Teng, David Quintanilla, Alexandra East-Seletsky, Evan R. Williams, and David F. Savage Biochemistry 2016 55 (24), 3461-3468 DOI: 10.1021/acs.biochem.6b00294
- Lee, T-H, Carpenter, TS, D'haeseleer, P, Savage, DF, Yung, MC. Encapsulin carrier proteins for enhanced expression of antimicrobial peptides. Biotechnology and Bioengineering. 2020; 117: 603– 613. https://doi.org/10.1002/bit.27222
- Jones JA, Giessen TW. Advances in encapsulin nanocompartment biology and engineering. Biotechnol Bioeng. 2021;118(1):491-505. doi:10.1002/bit.27564