Difference between revisions of "Team:NCKU Tainan/Human Practices"

 
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<img src="https://static.igem.org/mediawiki/2021/3/35/T--NCKU_Tainan--human_practice.png" width="70%"style="display:block; margin:auto;" />
 
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                    <h3>Design</h3>
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                        <a href="#">Read More</a>
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                    <h3>Code</h3>
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                        <a href="#">Read More</a>
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                    <h3>Launch</h3>
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                        <a href="#">Read More</a>
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     <main style="margin-top:5rem;" class="overall-1">
 
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        <section class="color-block justify-content-center">
             <h2 align="center" style="margin-bottom: 1rem; color:#332E2D">Overview</h2>
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             <h2 align="left" style="margin-bottom: 1rem; color:#332E2D; background:#FFFBF3">Overview</h2>
            <p align="center">   Sometimes as scientists, we tend to forget the world outside the lab. Innovations succeed inside the laboratory doesn’t mean it can be applied to the real world. An important aspect we need to consider is how our technology can be applied in society. Thus, human practice became one of the major pillars of our project, to test our project against the challenges in the real world. We believe that only through working with both professionals and consumers can we ensure that our product is beneficial to all. Our approach to human practices involved working with both professionals and the general public to understand their opinions and tailoring our project to meeting their demands. Through our interactions, we get to explore different aspects of the project that we would otherwise ignore, including intellectual property, sustainability, laws, and regulations.</p>
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          <p align="center">&emsp;&emsp;Communicating science to the public is not an easy task; sometimes, we need to adjust how we deliver our research to various audiences. We also need to understand what benefit the audience will receive from the systems and technology we bring. Therefore, Human Practices became an indispensable part of our project, which acts as a bridge between researchers and general audience or even experts in different fields. </p>
                <p>   The world is changing daily, and with it, talents, skills, and experience needs to be a part of that growth cycle too. With the growing controversy on GMOs and live therapeutics, we realized our iGEM project is at the heart of this discussion. The research and results on live therapeutics are few and far between, with it only being brought to attention these past few years. There are still so many challenges and obstacles live therapeutics have to face before it is widely accepted as a treatment method. We realized that no matter how much research we do, we ended with more questions unanswered than answered. Can we make it out onto the market, and survive in the harsh and competitive environment? How do we ensure our product’s viability in the market? What is the current stance of the world when it comes to living therapeutics? To ensure we are able to finalize the different aspects of our products, we decided to turn to different aspects of society, engaging with doctors, nurses, researchers, professionals involved in the legal and business side of drug and device development, patients, students, and the general public.</p>
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          <p>&emsp;&emsp;By closely collaborating with professionals and profoundly investigating the potential consumers' demands, we ensure our product development is beneficial to our community. We constructed a framework for our human practice project that can be categorized into two main parts: business promotion and education. We reached out to several experts to optimize our product and constructed our business model while considering intellectual property, laws, and regulations for business promotion. To mature our designs, we turned to doctors, researchers, and experts in product development for advice. </p>
                <p>   Thus, we visited places like dialysis centers, laboratories, biotech companies and also IPO (Intellectual Property Office) to learn from experts in their fields, and understand more on how to improve our project.</p>
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          <p>&emsp;&emsp;The educational section was a collective set targeting several audiences to spread information about synthetic biology. We attempted to discover multiple approaches and viable options to promote our products and collect feedback from our audiences. </p>
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                 <h2 class="bold-font">Expert visits</h2>
 
                 <h2 class="bold-font">Expert visits</h2>
 
                 <HR style="border-width: 5px;"></HR>
 
                 <HR style="border-width: 5px;"></HR>
                 <p>   Before we are able to get started on developing our idea into a product, we need to make sure that our idea is as close to perfect as possible, and that means tons of research and experiments. But, the real problem with many ideas, and perhaps the reason why many fail to become a success, is a lack of expertise. No matter how much time and effort we put into research, there will always be an expert who knows the topic or even industry much better than we do. So, to help further verify and improve our ideas, we visited several experts in different fields.</p>
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                 <p>&emsp;&emsp;Before we are able to get started on developing our idea into a product, we need to make sure that our idea is as close to perfect as possible, and that means tons of research and experiments. But, the real problem with many ideas, and perhaps the reason why many fail to become a success, is a lack of expertise. No matter how much time and effort we put into research, there will always be an expert who knows the topic or even industry much better than we do. So, to help further verify and improve our ideas, we visited several experts in different fields.</p>
 
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                 <section class="expert margin-top-5">
 
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                             <a class="nav-link tabname active" id="doctor-tab" data-toggle="tab" href="#doctor" role="tab" aria-controls="doctor" aria-selected="false"><span class="font-size-m" style="font-weight: bold;">Healthcare Expert Visits</span></a>
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                             <a class="nav-link tabname active" id="doctor-tab" data-toggle="tab" href="#doctor" role="tab" aria-controls="doctor" aria-selected="false"><span class="font-size-m" style="font-weight: bold;">Online Expert Meetup</span></a>
 
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                                             <h3 id="kuo">Dr. Te-Hui Kuo &emsp;4/15</h3>
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                                             <h3 id="kuo">Dr. Po-See Chen &emsp;5/28</h3>
                                             <h5>Attending Physician, Division of Nephrology, National Cheng Kung University Hospital</h5>
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                                             <h5>Director, Division of General Psychiatry, National Cheng Kung University Hospital</h5>
                                    <div class="row">
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                                  <h5>Professor, Institute of Behavioral Medicine, National Cheng Kung University</h5>
                                        <div class="col-lg">
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                                            <figure style="width: 100%;">
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                                                <a href="https://static.igem.org/mediawiki/2019/thumb/0/0c/T--NCKU_Tainan--HP_doctor4.png/800px-T--NCKU_Tainan--HP_doctor4.png" alt="doctor-kuo" target="blank" style="width:40%">
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                                  <div class="row">
                                                    <br><img src="https://static.igem.org/mediawiki/2019/thumb/0/0c/T--NCKU_Tainan--HP_doctor4.png/800px-T--NCKU_Tainan--HP_doctor4.png" alt="doctor-kuo" title="doctor-Kuo" style="width:100%">
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                                                </a>
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                                            </figure>
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                                            <p>&emsp;&emsp;We met with Dr. Po-See Chen online to obtain further knowledge about depression. He provided us with valuable insight and information regarding the characteristics of depression and the relation of depression with the gut. We met him during the early stages of our project, and he gave us a lot of valuable advice regarding the behavior of patients, such as self-diagnosis which is very dangerous among people who suffer from depression. By conducting this meeting, we can understand more regarding the nature of depression to continue with our project. He also gave advice regarding our education activities, encouraging us to better spread awareness regarding depression, which you can find in our <a href="https://2021.igem.org/Team:NCKU_Tainan/Communication">education page.</a></p>
                                        </div>
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                                        <div class="col-lg">
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                                <a href="https://static.igem.org/mediawiki/2021/5/5f/T--NCKU_Tainan--chenPo-See.png" target="blank" width="100%">
                                            <p><p>    We met with Dr. Te-Hui Kuo to gain knowledge about Chronic Kidney Disease. He provided us with invaluable insight into the connection between <i>p</i>-Cresol and Chronic Kidney Disease. We met with him during the early stages of the project, and he advised us to keep expanding on the idea of using blood measurement for uremic toxins. He also warned us that the public and even doctors don’t pay much attention to uremic toxins, which encouraged us to design activities to spread awareness, which you can find in our <a target="blank" href="https://2019.igem.org/Team:NCKU_Tainan/Public_Engagement">public engagement.</p></a>
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                                    <img src="https://static.igem.org/mediawiki/2021/5/5f/T--NCKU_Tainan--chenPo-See.png" alt=""width="70%">
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                                <!--container inside the intab-->
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                                <div class="container">
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                                            <h3>Dr. Junne-Ming Sung &emsp;6/25</h3>
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                                            <h5>Director and Attending Physician, Division of Nephrology, National Cheng Kung University Hospital</h5>
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                                    <div class="row">
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                                        <div class="col-lg">
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                                            <figure style="width: 100%;">
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                                                <a href="https://static.igem.org/mediawiki/2019/thumb/7/78/T--NCKU_Tainan--HP_doctor6.jpeg/800px-T--NCKU_Tainan--HP_doctor6.jpeg" alt="doctor-Sung" target="blank" style="width:40%">
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                                                    <br><img src="https://static.igem.org/mediawiki/2019/thumb/7/78/T--NCKU_Tainan--HP_doctor6.jpeg/800px-T--NCKU_Tainan--HP_doctor6.jpeg" alt="doctor-Sung" title="doctor-Sung" style="width:100%">
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                                                </a>
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                                        <div class="col-lg">
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                                            <p><p>    We met with Dr. Junne-Ming Sung to talk more about the viability of our device in the market. He guided us to think about the future of our device, highlighting several questions we had never thought of. His valuable insight allowed us to begin shifting the trajectory of our device to have a more functional role in the market. Instead of just being able to prove our biotherapeutic works, our device now has the potential to become a cornerstone in the diagnosis of Chronic Kidney Disease.
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                                            </p>
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                            <!--Nurse without pic-->
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                                <h3 id="huang">Ms. Li-Hui Huang &emsp;7/11</h3>
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                                <h5>Nurse, Chia Yi Chang Gung Memorial Hospital Dialysis Center</h5>
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                                <p>    In an activity hosted by Taiwan Chronic Kidney Disease Foundation, we had the opportunity to meet Ms. Li-Hui Huang. As someone who interacts with CKD patients on a daily basis, she was able to give us more insight on a CKD patient’s needs and wants. She talked us through the treatments that CKD patients undergo, mentioning that dialysis was often used as a prevention method for CKD patients, and they need to undergo dialysis three times a week. While uremic toxins and uric protein checks are important for CKD patients, they do not do routine checks on it - and even if they do, they only do creatinine checks once a month.</p>
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                                            <h3>Ms. Yu-Chen Kuo &emsp;8/29</h3>
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                                            <h5>Chronic Kidney Disease Nurse Specialist, National Cheng Kung University Hospital</h5>
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                                                <a href="https://static.igem.org/mediawiki/2019/4/4d/T--NCKU_Tainan--HP_nurse1.jpeg" alt="Ms. Guo" target="blank" style="width:200%">
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                                                    <br><img class="w-75 margin-auto" src="https://static.igem.org/mediawiki/2019/4/4d/T--NCKU_Tainan--HP_nurse1.jpeg" alt="Ms. Guo" title="doctor-Guo" style="width:200%">
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                                                </a>
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                                        <div class="col-lg">
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                                            <p><p>    As a CKD Nurse Specialist, she periodically give lectures on how to handle CKD patients and background knowledge on the disease, and thus, knows the disease very well. She taught us quite a lot about the disease, especially about the treatments. While there is no current treatment that can fully cure the patients, she does admit that the patients will sometimes take Chinese Herbal medicine or even go for acupuncture to give themselves a peace of mind. When we mentioned our project, she mentioned a current drug currently insured by National Health Insurance (NHI) that could be our market competitor. In order to make it in the Taiwanese market, she advised us to consider our drug being insured by NHI, as the government has policies regarding CKD in Taiwan, and thus insured most CKD treatments.
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                        </div>
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+
 
                         <div class="tab-pane fade" id="lab" role="tabpanel" aria-labelledby="lab-tab">
 
                         <div class="tab-pane fade" id="lab" role="tabpanel" aria-labelledby="lab-tab">
 
                             <div class="intab-layout">
 
                             <div class="intab-layout">
 
                                 <!--container inside the intab-->
 
                                 <!--container inside the intab-->
                                 <div class="container">
+
                                 <div class="container1">
                                             <h3>Professor Yi-Je Juang</h3>
+
                                             <h3>Professor Yu-Cheng Lin</h3>
                                             <h5>Professor, Department of Chemical Engineering, National Cheng Kung University</h5>
+
                                             <h5>Professor, Department of Engineering Science, National Cheng Kung University </h5>
 
                                     <div class="row">
 
                                     <div class="row">
 
                                         <div class="col-lg-4">
 
                                         <div class="col-lg-4">
 
                                             <figure class="justify-content-center align-items-center" style="width: 100%;">
 
                                             <figure class="justify-content-center align-items-center" style="width: 100%;">
                                                 <a  href="https://static.igem.org/mediawiki/2019/thumb/0/0d/T--NCKU_Tainan--HP_doctor5.jpeg/578px-T--NCKU_Tainan--HP_doctor5.jpeg" alt="prof-Juang" target="blank" style="width: 100%;" >
+
                                                 <a  href="https://static.igem.org/mediawiki/2021/7/7b/T--NCKU_Tainan--Professor_Lin.jpg" alt="prof-Lin" target="blank" style="width: 100%;" >
                                                   <br><img src="https://static.igem.org/mediawiki/2019/thumb/0/0d/T--NCKU_Tainan--HP_doctor5.jpeg/578px-T--NCKU_Tainan--HP_doctor5.jpeg" alt="prof-Juang" title="prof-Juang" style="width:100%;height:30%;">
+
                                                   <br><img src="https://static.igem.org/mediawiki/2021/7/7b/T--NCKU_Tainan--Professor_Lin.jpg" alt="prof-Lin" title="prof-Lin" style="width:100%;height:50%;">
 
                                                 </a>
 
                                                 </a>
 
                                             </figure>
 
                                             </figure>
 
                                         </div>
 
                                         </div>
 
                                         <div class="col-lg-8">
 
                                         <div class="col-lg-8">
                                            <p><p>   While we were testing PDMS chip, we encountered a problem. When we injected whole blood into the blood separation chamber, the blood would flow into the reaction chamber instantly, causing impureness of the plasma. We hope to stop this from happening so we went to Professor Juang to ask suggestions toward our microfluidic wafer. He suggested us to apply a passive valve on the channel between the whole blood chamber and the reaction chamber. The passive valve can stop the flow of the blood without incurring any additional operation, which improved the purity of the plasma we gained significantly. Furthermore, He told us to retry on the PDMS spinning test (the PDMS would burst during centrifuge at that time) since theoretically, PDMS layers should strongly adhere together and it should be inseparable. Also, he suggested us to use double-sided tape in the combination of the acrylic disc, which is proved to be effective. By having a fruitful meeting with him, we restored our faith in PDMS and improved our project by applying passive valve and double-sided tape in the microfluidic disc.
+
                                          <br>
                                            </p>
+
                                            <p>&emsp;&emsp;Our first hardware idea was to detect human stress levels through saliva, we planned to extract cortisol which is the biomarker of stress, by detecting cortisol levels throughout a couple of days, we will be able to determine someone’s depression level. We made several discussions with professor Yu-Cheng Lin due to the fact that he has the real experience of extracting the different substances from saliva and detect the concentration of several substances through the paper-based electrochemical device. We wanted to continue and make this concept a reality, but suddenly covid-19 strikes Taiwan, so we were not able to go into any lab and we finally suspend the idea then search for another alternative.</p>
 
                                         </div>
 
                                         </div>
 
                                     </div>
 
                                     </div>
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                             <div class="intab-layout">
 
                             <div class="intab-layout">
 
                                 <!--container inside the intab-->
 
                                 <!--container inside the intab-->
                                 <div class="container">
+
                                 <div class="container1">
                                             <h3>Professor Chia-Yuan Chen</h3>
+
                                             <h3>Professor Chung-Hsien Wu</h3>
                                             <h5>Associate Professor, Department of Mechanical Engineering, National Cheng Kung University</h5>
+
                                             <h5>Professor, Department of Computer Science, National Cheng Kung University </h5>
 
                                     <div class="row">
 
                                     <div class="row">
 
                                         <div class="col-lg-4">
 
                                         <div class="col-lg-4">
 
                                             <figure style="width: 100%;margin:0 auto;">
 
                                             <figure style="width: 100%;margin:0 auto;">
                                                 <a href="https://static.igem.org/mediawiki/2019/thumb/0/00/T--NCKU_Tainan--HP_doctor2.jpeg/455px-T--NCKU_Tainan--HP_doctor2.jpeg" alt="prof-Chen" target="blank" style="width: 100%;" >
+
                                                 <a href="https://static.igem.org/mediawiki/2021/2/2d/T--NCKU_Tainan--Professor_Wu.jpg" alt="prof-Wu" target="blank" style="width: 100%;" >
                                                     <br><img src="https://static.igem.org/mediawiki/2019/thumb/0/00/T--NCKU_Tainan--HP_doctor2.jpeg/455px-T--NCKU_Tainan--HP_doctor2.jpeg" alt="prof-Chen" title="prof-Chen" style="width:100%;height: 30%;">
+
                                                     <br><img src="https://static.igem.org/mediawiki/2021/2/2d/T--NCKU_Tainan--Professor_Wu.jpg" alt="prof-Wu" title="prof-Wu" style="width:100%;height: 30%;">
 
                                                 </a>
 
                                                 </a>
 
                                             </figure>
 
                                             </figure>
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                                         <div class="col-lg-8">
 
                                         <div class="col-lg-8">
 
                                             <br>
 
                                             <br>
                                             <p>   We proposed our idea about creating a device using microfluidic chips in mind, however we were not exactly sure how to apply the chip into our device. Professor Chen was very helpful as he discussed with us about the type of microfluidic chip that can be used in our device, how the chip will integrate with other parts of the device, and whether our chip is reusable or not. He told us to try using PDMS chip because it’s affordable and it has the same performance as acrylic chip. From this discussion, we then decided to use PDMS-based microfluidic chip. Professor Chen then provided us with resources in his lab and taught us the required PDMS chip fabrication skills. By his help, we successfully made a few version of <a href="https://2019.igem.org/Team:NCKU_Tainan/Hardware#headingPDMS">PDMS microfluidic chips.</a></p>
+
                                             <p>&emsp;&emsp;Due to the fact that covid-19 in Taiwan escalated very quickly, we were thinking to find another way to build something even that we are not present physically. Then, we had an idea to made an artificial intelligence that can automatically detect depression using sound, and because none of our team members is from the Department of computer science we asked for guidance from Prof. Chung-Hsien Wu in developing the artificial intelligence.</p>  
                                        </div>
+
                                      </div>
 
                                     </div>
 
                                     </div>
 
                                 </div>
 
                                 </div>
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                             <div class="intab-layout">
 
                             <div class="intab-layout">
 
                                 <!--container inside the intab-->
 
                                 <!--container inside the intab-->
                                 <div class="container">
+
                                 <div class="container1">
                                             <h3>Professor Ruey-Jen Yang</h3>
+
                                             <h3>Professor Chien-Hsiang Chang</h3>
                                             <h5>Chair Professor, Department of Engineering Science, National Cheng Kung University</h5>
+
                                             <h5>Professor, Department of chemical engineering, National Cheng Kung University</h5>
 
                                     <div class="row">
 
                                     <div class="row">
 
                                         <div class="col-lg-4">
 
                                         <div class="col-lg-4">
 
                                             <figure style="width: 100%;margin:0 auto;">
 
                                             <figure style="width: 100%;margin:0 auto;">
                                                 <a href="https://static.igem.org/mediawiki/2019/d/d2/T--NCKU_Tainan--HP_doctor3.jpeg" alt="prof-Yang" target="blank" style="width: 100%;" >
+
                                                 <a href="https://static.igem.org/mediawiki/2021/3/3f/T--NCKU_Tainan--Professor_Chang.jpg " alt="prof-Chang" target="blank" style="width: 100%;" >
                                                     <br><img src="https://static.igem.org/mediawiki/2019/d/d2/T--NCKU_Tainan--HP_doctor3.jpeg" alt="prof-Yang" title="prof-Yang" style="width:100%;height: 30%;">
+
                                                     <br><img src="https://static.igem.org/mediawiki/2021/3/3f/T--NCKU_Tainan--Professor_Chang.jpg " alt="prof-Chang" title="prof-Chang" style="width:100%;height: 30%;">
 
                                                 </a>
 
                                                 </a>
 
                                             </figure>
 
                                             </figure>
 
                                         </div>
 
                                         </div>
 
                                         <div class="col-lg-8">
 
                                         <div class="col-lg-8">
                                            <p><p>   We consulted Professor Yang when we kept failing on creating the PDMS microfluidic chip as the runner joint made of PDMS will rupture during centrifugation process. Although the third version of the wafer is reinforced at the joint, we still hope to find an alternative before the third version of the wafer comes out. Since Professor Yang has done low-cost paper-based chip development and micro-flow channel design, we hoped to get help and his advice in this regard.</p>   
+
                                          <br>
                                            <p>    After asking and briefly describing what we wanted to do, he suggested us to find his student who was doing a PDMS-related study. He told us that the bond between PDMS and PDMS is weaker than the bond between PDMS and glass and acrylic. It is recommended that we try to use PDMS and acrylic binding to test whether the strength could have a higher performance. Other problems also include the parameters of the oxygen plasma during binding that will also affect the binding effect (the pressure and time of the binding).  Professor Yang then suggested that we make the whole acrylic disc into a microfluidic disc, which will save some space and fixed processes and introduced Ph.D. Weng to us. By his suggestion, we went to Ph.D. Weng and tested acrylic materials for bonding in our third version of the device.
+
                                            <p>&emsp;&emsp;Before settling with our current procedure of manufacturing Menbels, we wanted to make sure that our procedure and knowledge are sufficient for us to meet the requirements and make our system feasible to work. And professor Chien-Hsiang Chang has experience in making alginate layers to wrap several substances, Prof. Chang also ensures us that our plan is feasible and isn’t very hard to perform.</p>
                                            </p>
+
                                        </div>
+
                                    </div>
+
                                </div>
+
                            </div>
+
                            <div class="intab-layout">
+
                                <!--container inside the intab-->
+
                                <div class="container">
+
                                            <h3>Ph.D. Chen-Hsun Weng</h3>
+
                                            <h5>Chief of Industry-Academic Collaboration in Medical Device Innovation Center, Tainan</h5>
+
                                    <div class="row">
+
                                        <div class="col-lg-4">
+
                                            <figure style="width: 100%;margin:0 auto;">
+
                                                <a href="https://static.igem.org/mediawiki/2019/8/81/T--NCKU_Tainan--HP_doctor1.jpeg" alt="prof-Weng" target="blank" style="width: 100%;" >
+
                                                    <br><img src="https://static.igem.org/mediawiki/2019/8/81/T--NCKU_Tainan--HP_doctor1.jpeg" alt="prof-Weng" title="prof-Weng" style="width:100%;height:30%;">
+
                                                </a>
+
                                            </figure>
+
                                        </div>
+
                                        <div class="col-lg-8">
+
                                            <p><p>    We went to Ph.D. Weng to learn about paper-based microfluidic chip and how to use acrylic engraving machine and we also consulted about what type of microfluidic chip suit us the best. We had tested our device parts and found some troubles regarding the chip we used. Our first version uses PDMS microfluidic chip but apparently when we tested it in our centrifuge, it burst. Therefore we went to Ph.D. Chen-Hsun Weng who suggested us to use paper-based chip because it can do blood separation. He also said PDMS is harder to customize and is quite inefficient. He then taught us to use the engraving machine for the acrylic disk.
+
                                            </p>
+
 
                                         </div>
 
                                         </div>
 
                                     </div>
 
                                     </div>
 
                                 </div>
 
                                 </div>
 
                             </div>
 
                             </div>
 +
                         
 
                         </div>
 
                         </div>
 
                     </div>
 
                     </div>
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                 <h2 class="bold-font">Enterprise visit</h2>
 
                 <h2 class="bold-font">Enterprise visit</h2>
 
                 <HR style="border-width: 5px;"></HR>
 
                 <HR style="border-width: 5px;"></HR>
                 <p>   Just because an idea is good does not always mean it will sell well in the market. Our product may be designed and modified in the laboratory and adjusted to maximize its performance. However, we needed advice from potential stakeholders to ensure our product will meet real-world demands. We need to interact with industries to understand more about the industrial environment and current market situation. So, in order to refine our idea into a product suitable for the market, we visited several enterprises.
+
                 <p>&emsp;&emsp;Just because an idea is good does not always mean it will sell well in the market. Our product may be designed and modified in the laboratory and adjusted to maximize its performance. However, we needed advice from potential stakeholders to ensure our product will meet real-world demands. We need to interact with industries to understand more about the industrial environment and current market situation. So, in order to refine our idea into a product suitable for the market, we visited several enterprises.
 
                 </p>
 
                 </p>
 
                 <!--Start of tabbed-->
 
                 <!--Start of tabbed-->
                <section class="enterprise margin-top-5">
+
                <section class="enterprise margin-top-5">
 
                     <ul class="nav nav-tabs" id="myTab" role="tablist">
 
                     <ul class="nav nav-tabs" id="myTab" role="tablist">
 
                         <li class="nav-item">
 
                         <li class="nav-item">
                             <a class="nav-link tabname active" id="geneferm-tab" data-toggle="tab" href="#geneferm" role="tab" aria-controls="geneferm" aria-selected="true"><span class="font-size-m" style="font-weight: bold;">GeneFerm</span></a>
+
                             <a class="nav-link tabname active" id="geneferm-tab" data-toggle="tab" href="#geneferm" role="tab" aria-controls="geneferm" aria-selected="true"><span class="font-size-m" style="font-weight: bold;">Trade wind biotech</span></a>
                        </li>
+
                        <li class="nav-item">
+
                            <a class="nav-link tabname" id="genemont-tab" data-toggle="tab" href="#genemont" role="tab" aria-controls="genemont" aria-selected="false"><span class="font-size-m" style="font-weight: bold;">GenMont</span></a>
+
                        </li>
+
                        <li class="nav-item">
+
                            <a class="nav-link tabname" id="synbio-tab" data-toggle="tab" href="#synbio" role="tab" aria-controls="synbio" aria-selected="false"><span class="font-size-m" style="font-weight: bold;">Synbio Tech</span></a>
+
 
                         </li>
 
                         </li>
 
                         <li class="nav-item">
 
                         <li class="nav-item">
                             <a class="nav-link tabname" id="winston-tab" data-toggle="tab" href="#winston" role="tab" aria-controls="winston" aria-selected="false"><span class="font-size-m" style="font-weight: bold;">Winston</span></a>
+
                             <a class="nav-link tabname" id="genemont-tab" data-toggle="tab" href="#genemont" role="tab" aria-controls="genemont" aria-selected="false"><span class="font-size-m" style="font-weight: bold;">Chen En Food Product Enterprise Co., Ltd</span></a>
 
                         </li>
 
                         </li>
 
                         <li class="nav-item">
 
                         <li class="nav-item">
                             <a class="nav-link tabname" id="nar-tab" data-toggle="tab" href="#nar" role="tab" aria-controls="nar" aria-selected="false"><span class="font-size-m" style="font-weight: bold;">NARLabs</span></a>
+
                             <a class="nav-link tabname" id="synbio-tab" data-toggle="tab" href="#synbio" role="tab" aria-controls="synbio" aria-selected="false"><span class="font-size-m" style="font-weight: bold;">8D Tea Fresh Kitchen</span></a>
 
                         </li>
 
                         </li>
 +
                     
 
                     </ul>
 
                     </ul>
 
                     <div class="tab-content" id="myTabContent">
 
                     <div class="tab-content" id="myTabContent">
 
                         <div class="tab-pane fade show active" id="geneferm" role="tabpanel" aria-labelledby="geneferm-tab">
 
                         <div class="tab-pane fade show active" id="geneferm" role="tabpanel" aria-labelledby="geneferm-tab">
                             <h3>GeneFerm Biotechnology Co., LTD.</h3>
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                             <h3>Trade Wind Biotech</h3>
                             <p>   Geneferm is a leading fermentation company, that focuses on fermented fungi, microbes and also probiotics. We visited Geneferm to learn more about the criteria we need to meet before our product can enter the market. At this stage, we were still considering whether to market our product as a drug or probiotic.</p>
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                             <p>&emsp;&emsp;Trade Wind Biotech (TWBIO) is a pioneer company based in Taiwan that implements synthetic biology as its core technique. We were allowed to visit their factory and laboratory led by Dr Lance, the CEO of TWBIO. We also invited team CCU_Taiwan to join us on this trip, and both of our teams received a lot of feedback from Dr Lance regarding entrepreneurship and presentation skills.</p>
                            <p>    From our meeting with Miss Erin Wu and Mr Eugene Wu, we learned:</p>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Quality control of a living cell on a medication</li>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Food Industry Research and Development (FIRDI) help in inspection of the supplement</li>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Comparison between food and medication process and regulation</li>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">The risks if we do not apply patent for our drug or medical device</li>
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                            <p>    Moreover, they suggested us three things:</p>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Determine the usage of product like the age group and delivering product</li>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Take into account the law and regulations since Taiwan does not have proper gene-editing regulations especially toward the biotherapeutic drug</li>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Education toward GMO usage</li>
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                            <p>By their suggestions, we conducted survey for our drug method delivery and classified approximate age of ESRD patients who will consume our biotherapeutic drug (Data can be seen in our <a href="https://2019.igem.org/Team:NCKU_Tainan/Entrepreneurship#method-Deliver" target="blank">entrepreneurship</a>. Also, because of them, we also planned to pay a visit to IPO (Intellectual Property Office) to learn more about patents.</p>
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                             <h3>GenMont Biotech Inc.</h3>
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                             <h3>Chen En Food Product Enterprise Co., Ltd</h3>
                             <p>   Genmont is a leading probiotic company in Taiwan, where we had our first enterprise visit and we were fortunate enough to meet Genmont’s Miss Tsai, Wan-Hua, Miss Mei-Ling Wang, Miss Janette Chen. As this enterprise visit was made when we still wanted our product to be a probiotic, our main purpose of visiting GenMont is to learn about how probiotic is made, how quality management is done and regulations we need to obey in applying this product to the market. </p>
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                             <p>&emsp;&emsp;Our team was honoured to interview the general manager of Chen En Food Product Enterprise, Mr Vincent, as Chen En is one of the largest bubble suppliers in both local and global markets. Before the online interview session began, we signed a Memorandum of Understanding (MOU) with them. As a giant bubble supplier, they provided advice on preparing our bubble with the engineered bacteria inside. In addition, they also gave us valuable market data to further our business model.</p>
                            <p>    They were kind enough to give a short talk about how their company works and how their research and development works. They also talked about their process in entering their product into the market. This way, we were able to get a glimpse of how the company is able to build from the ground up, and inspired us to create a business plan for our products.</p>
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                            <p>    Through this visit, we received a lot of feedback and realized we need to much more research, not only on developing our product, but also more research on many other fields. We need to start thinking about how to apply this project into a real life situation. We need to consider the regulations and consider adding our product into the National Health Insurance.They also mentioned about the safety assay on how our engineered E.coli is and by their suggestions, we optimized our <a href="https://2019.igem.org/Team:NCKU_Tainan/Design#Subtitle3" target="blank">kill switch</a> plan and run a functional check to make sure that our engineered E.coli is safe.</p>
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                                 <a href="https://static.igem.org/mediawiki/2019/thumb/3/3f/T--NCKU_Tainan--HP_genemont.jpeg/800px-T--NCKU_Tainan--HP_genemont.jpeg" target="blank">
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                                     <img src="https://static.igem.org/mediawiki/2019/thumb/3/3f/T--NCKU_Tainan--HP_genemont.jpeg/800px-T--NCKU_Tainan--HP_genemont.jpeg" alt="genemont">
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                                     <img src="https://static.igem.org/mediawiki/2021/5/5f/T--NCKU_Tainan--chenen.png" alt="genemont">
 
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                             <h3>Synbio Tech Inc.</h3>
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                             <h3>8D Tea Fresh Kitchen</h3>
                             <p>   Synbio Tech Inc., a company focusing on probiotic powder and healthcare products. We got a chance to meet Mr. Jin-Seng Lin, Miss I-Ju Chang and Miss Erica Chang from Synbio Tech. Our purpose is to have valuable insights on how we are going to market the product and manufacture process. We implemented the marketing suggestion from Synbio Tech to expand our products marketing and business plan. It was an enlightenment meeting, we received a lot of suggestions on how we should market our products:</p>
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                             <p>&emsp;&emsp;We visited a local handmade bubble tea shop in Nantou and their IoT live kitchen to learn more about bubble production and marketing. They also suggested we market our product as chilled ready-to-eat (RTE) food, allowing us to position it in the market correctly. We also witnessed how they made bubbles from scratch and learned of the sterilization and bubble heating process. For more details, please click on the file below!
                                <ol>
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</p>
                                <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Establish the key points of the products</li>
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                              <form action="https://static.igem.org/mediawiki/2021/8/89/T--NCKU_Tainan--8Dtea.pdf" target="_blank">
                                <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Marketing Promotion has to be different since our products are different and have a specific target. They also mentioned our drug marketing is also limited as we have target consumers. However, they did mention B2B (Business to Business):</li>
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                                <div align="center"><button type="submit" style="background-color:#6A8DC3;color:#FFFAF4; border: 1px #F4DBB2;font-weight: bold;"class="font-size-m">Link for more details</button></div>
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      </form>
                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Join medical conferences to meet potential business partners and auiliences</li>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">The website design must be appealing and have a clear description</li>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">White paper to attract investors</li>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Proper and effective advertisements</li>
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                                    <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Drug must fulfill cGMP requirements, and have their form. They told us that from powder, liquid and tablets form of the drug, the most popular one is the powder sachet but to determine which one is suitable for us, we need to conduct a survey for prices and forms. By their suggestions, we started our survey about <a target="blank" href="https://2019.igem.org/Team:NCKU_Tainan/Entrepreneurship">public opinions. </li></a>
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                            <h3>Winston Medical Supply Co.</h3>
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                            <p>    We went to Winston Medical Supply Co. to learn about the drugs market and the steps needed to be taken for a drug to be in the market. We were able to meet with Yu-Cheng Wang, CEO of the company and also Yi-Ching Chen, Marketing Director of Winston. We received a lot of feedback toward our wet and entrepreneurship part. He agreed that CKD is a serious problem in Taiwan and uses up a lot of money to deal with the treatments, but they were concerned about how we are going to maintain the effectiveness of <i>Can</i> gene knockout, but after we showed them how we did a functional test, they then suggested it needs to be optimized later when we already finished with the fermentation and packaging part in the future.</p>
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            </div>
                            <p>    Moving on to the marketing part, we showed them our CreSolve living therapeutic drug flowchart that includes the few steps we need to take in order to make our living therapeutic successful in the market. Wang CEO emphasized that we need to start from API (Active Pharmaceutical Ingredients), and it needs to be divided into 4 parts which are Regulation, API, Formulation and Preclinical. After that, we then can develop our drug more precisely. Through their recommendations, we came up with a new flowchart of our CreSolve living therapeutic drug:</p>
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                                    <img src="https://static.igem.org/mediawiki/2019/archive/7/75/20191020172517%21T--NCKU_Tainan--HP_businessModel.png" alt="Bmodel">
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                            <p>    We also asked whether they can be our potential partners regarding drug manufacturing in the future, they said it is possible as long we can show them the final prototype of our CreSolve living therapeutic drug accompanied by government approval and research data.</p>
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                            <h3>NARLabs (National Applied Research Laboratories)</h3>
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                            <p>    Founded by the government, NARLabs is one of the leading research centers in Taiwan. We had the opportunity to visit the lab and consulted our business model with NARLabs’ startup team, which is aimed at helping new startups to build better business model and also provide fundings to potential startups. During the visit, we talked about the overall project of OMG and also showed them the current business model we had. </p>
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                            <p>    The meeting was successful and we gained a lot from NARLabs, mostly from the business part:</p>
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                                <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Currently, laws in Taiwan on engineered bacteria are quite strict and there are still some laws under discussion. So, we should pay more attention to the laws and make sure we are always up-to-date with the latest news.</li>
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                                <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">Coating the sensing bacteria on PDMS chips may be a good idea, but we need to be extra careful about the bacteria because most bacteria have a certain condition that has to be met in order to survive.</li>
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          </a>
                                <li style="padding-left:1em; font-size: 1rem; line-height: 1.5;">When developing the business model, sometimes it is also important to consider users’ experiences into the model. For example, where will the sensing device best serve our patient and if the device is safe enough to let the patients operate it by themselves.</li>
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                 <h2 class="bold-font" style="text-align: center;color: #973A41;">2019 NCKU iGEM OMG Survey</h2>
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                 <h2 class="bold-font" style="text-align: center;color: #355489;">2021 NCKU iGEM Survey</h2>
 
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                 <p>   Genetically Modified Organisms (GMOs) are becoming more and more prevalent in our society due to its potential in many different fields, including pharmaceutical field. There is a large amount of misconceptions and controversies surrounding GMOs. Despite the majority of scientists and researchers pushing for GMOs, it seems like the public are getting more and more wary about it.
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                 <p>&emsp;&emsp;Genetically Modified Organisms (GMOs) are becoming more prevalent in our society due to their wide range of potential applications. Although more research has been conducted regarding the safety of GMOs, many still believe that GMOs are not safe, and it remains to be a controversial topic among society. </p>
                </p>
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                 <p>&emsp;&emsp;To better understand how the public perceives GMOs and mental health issues, we conducted an online survey. Through the survey, we were able to collect hundreds of respondents’ opinions along with their feedback on our project.</p>
                 <p>   In order to have a better idea of how the public perceives GMOs in the context of our Oh My Gut project, we developed an opinion survey about GMOs and their use in the treatment of CKD. We were fortunate enough to be able to spread this survey to international citizens. We received responses from Singapore, Malaysia, Indonesia, Japan, the Netherlands, Germany, Ukraine, Spain, Mexico, China, Canada, India and Greece.
+
                </p>
+
 
                 <!--Each part of survey-->
 
                 <!--Each part of survey-->
 
                 <!--Survey---1-->
 
                 <!--Survey---1-->
 
                 <section>
 
                 <section>
                     <h3 class="center-font margin-top-5">Population Sample</h3>
+
                     <h3 class="center-font margin-top-5">Sample Demographics </h3>
 
                     <hr class="hr-half">
 
                     <hr class="hr-half">
                     <p>&emsp;From the responses we got, we know that nearly 80% of responses were comprised of those aged 18 - 25 and 41 - 65 (see Fig. 1). It was relieving to know that a large majority has received high school-level education at the very least (see Fig. 2), although only 19% were of scientific backgrounds (see Fig. 3).
+
                     <p>&emsp;&emsp;73.3% of our respondents were young adults aged between 18-29 years old, education levels between highschool to university. </p>
                    </p>
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            <div class="container-fluid p-0">
                    <div class="container">
+
                         <div class="row no-gutters">
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                             <div class="col-lg ">
                             <div class="col-md-4 col-12">
+
                                 <figure class="d-flex flex-column justify-content-center align-items-center px-lg-3">
                                 <figure class="figure-default-100">
+
                         
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/7/74/T--NCKU_Tainan--IHP_graph_1.png" style="width: 125%;">
+
                               
                                        <img src="https://static.igem.org/mediawiki/2019/7/74/T--NCKU_Tainan--IHP_graph_1.png" alt="survey-1" title="survey-1" style="width: 125%;">
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                                <a href="https://static.igem.org/mediawiki/2021/9/9e/T--NCKU_Tainan--surveyresults1.png" target="blank" width="70%">
                                    </a>
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                                    <img src="https://static.igem.org/mediawiki/2021/9/9e/T--NCKU_Tainan--surveyresults1.png" alt="" width="100%">
                                </figure>
+
                                </a>
                                <figcaption class="center"><p><p>Fig. 1. Age distribution</p></figcaption>
+
                         
 +
                              </figure>
 
                             </div>
 
                             </div>
                            <div class="col-md-4 col-12">
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                        </div>
                                <figure class="figure-default-100">
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              </div>
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/c/c7/T--NCKU_Tainan--IHP_graph_2.png" style="width: 125%;">
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                                        <img src="https://static.igem.org/mediawiki/2019/c/c7/T--NCKU_Tainan--IHP_graph_2.png" alt="survey-2" title="survey-2" style="width: 125%;">
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                                    </a>
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                                </figure>
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                                <figcaption class="center"><p><p>Fig. 2. Highest education level</p></figcaption>
+
                            </div>
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                            <div class="col-md-4 col-12">
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                                <figure class="text-center figure-default-100">
+
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/7/72/T--NCKU_Tainan--IHP_graph_3.png" style="width: 125%;">
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                                        <img src="https://static.igem.org/mediawiki/2019/7/72/T--NCKU_Tainan--IHP_graph_3.png" alt="survey-3" title="survey-3" style="width: 125%;">
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                                    </a>
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                                </figure>
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                                <figcaption class="center"><p><p>Fig. 3. Background</p></figcaption>
+
                            </div>
+
                        </div>
+
                    </div>
+
 
                 </section>
 
                 </section>
 
                 <!--Survey---2-->
 
                 <!--Survey---2-->
 
                 <section>
 
                 <section>
                     <h3 class="center-font margin-top-10">Knowledge on CKD</h3>
+
                     <h3 class="center-font margin-top-10">Understanding</h3>
 
                     <hr class="hr-half">
 
                     <hr class="hr-half">
                     <p>   First, we wanted to assess the sample population’s general knowledge of Chronic Kidney Disease. Thus, we established several questions to learn more about their level of information. It was quite a surprise to us that only 47% of them had heard of CKD (see Fig. 4) and only 10% admits to being quite knowledgeable about CKD (see Fig. 5). When asked about current treatments for CKD (see Fig. 6), 58% admitted to knowing nothing. The most well-known method was dialysis and kidney transplant, with 22% and 11% responses respectively. Other responses include medicine, diet control, controlling blood pressure/sugar and active charcoal.
+
                     <p>&emsp;&emsp;As we mentioned above, we wanted to collect the public’s views on mental health issues. Therefore, we divided the respondents into those who have suffered from depression and those who have not. For those who have experienced depressive symptoms, we asked more follow-up questions. 54.5% answered that the primary cause of their depression is stress. Apart from this, we also asked about their opinions about the current solution to depression. The answers were relatively evenly distributed, with concerns about side effects, low effectiveness, and price.</p>
                    </p>
+
                  <div class="container-fluid p-0">
                    <p>    From these responses, we could deduce that there is still a lack of education and knowledge when it comes to Chronic Kidney Disease. The responses inspired us to launch a workshop aimed at elementary students, to educate them about kidneys with a hands-on approach. (See <a href="https://2019.igem.org/Team:NCKU_Tainan/Public_Engagement" target="_blank">public engagement</a>)
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                         <div class="row no-gutters">
                    </p>
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                             <div class="col-lg ">
                    <div class="container">
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                                 <figure class="d-flex flex-column justify-content-center align-items-center px-lg-3">
                         <div class="row">
+
                         
                             <div class="col-md-4 col-12">
+
                               
                                 <figure class="figure-default-100">
+
                                <a href="https://static.igem.org/mediawiki/2021/8/87/T--NCKU_Tainan--surveyresults2.png" target="blank" width="70%">
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/d/dc/T--NCKU_Tainan--IHP_graph_4.png" style="width: 125%;">
+
                                    <img src="https://static.igem.org/mediawiki/2021/8/87/T--NCKU_Tainan--surveyresults2.png" alt="" width="100%">
                                        <img src="https://static.igem.org/mediawiki/2019/d/dc/T--NCKU_Tainan--IHP_graph_4.png" alt="survey-4" title="survey-4" style="width: 125%;">
+
                                </a>
                                    </a>
+
                         
                                </figure>
+
                              </figure>
                                <figcaption class="center"><p><p>Fig. 4. Have you heard of CKD?</p></figcaption>
+
 
                             </div>
 
                             </div>
                            <div class="col-md-4 col-12">
+
                        </div>
                                 <figure class="figure-default-100">
+
              </div>
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/8/84/T--NCKU_Tainan--IHP_graph_5.png" style="width: 125%;">
+
                              <div class="container-fluid p-0">
                                        <img src="https://static.igem.org/mediawiki/2019/8/84/T--NCKU_Tainan--IHP_graph_5.png" alt="survey-5" title="survey-5" style="width: 125%;">
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                        <div class="row no-gutters">
                                    </a>
+
                            <div class="col-lg ">
                                </figure>
+
                                 <figure class="d-flex flex-column justify-content-center align-items-center px-lg-3">
                                <figcaption class="center"><p><p>Fig. 5. What is your understanding of CKD? (5 being an expert on CKD)</p></figcaption>
+
                         
 +
                               
 +
                                <a href="https://static.igem.org/mediawiki/2021/c/cd/T--NCKU_Tainan--surveyresults3.png" target="blank" width="70%">
 +
                                    <img src="https://static.igem.org/mediawiki/2021/c/cd/T--NCKU_Tainan--surveyresults3.png" alt="" width="90%">
 +
                                </a>
 +
                         
 +
                              </figure>
 
                             </div>
 
                             </div>
                            <div class="col-md-4 col-12">
+
                        </div>
                                <figure class="figure-default-100">
+
              </div>
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/3/35/T--NCKU_Tainan--IHP_graph_6.png" style="width: 125%;">
+
                                        <img src="https://static.igem.org/mediawiki/2019/3/35/T--NCKU_Tainan--IHP_graph_6.png" alt="survey-6" title="survey-6" style="width: 125%;">
+
                                    </a>
+
                                </figure>
+
                                    <br>
+
                                <figcaption class="center-flex center"><p><p>Fig. 6. What are the current treatments for CKD?</p></figcaption>
+
                            </div>
+
                        </div>
+
                    </div>
+
 
                 </section>
 
                 </section>
 
                 <!--Survey---3-->
 
                 <!--Survey---3-->
                <section>
+
              <!-- <section>
                     <h3 class="center-font margin-top-10">Living Therapeutic Acceptance</h3>
+
                     <h3 class="center-font margin-top-10">GMOs Acceptance</h3>
 
                     <hr class="hr-half">
 
                     <hr class="hr-half">
                     <p>    Second, we wanted to assess the sample population’s acceptance when it comes to living therapeutic. Thus, we established a few questions to understand more about their stance on living therapeutic (engineered bacteria used as medical treatments). Only 37% were supportive of genetic engineering, while 31% were considerably neutral (see Fig. 7). 39% approved the development of ‘gene-edited’ bacterial drugs, while only 34% agreed to use said bacterial drugs.
+
                     <p>    Since our product is also categorized as GMOs, we asked the respondents how they perceived GMOs in the survey. Naturally, safety issues came up first, with more than half of the respondents agreeing on them as the main worry in GMO based products. However, when we asked them to rate their understanding of synthetic biology on a scale of 1-10, the average outcome was only 3.8. Therefore, we could deduce that lack of understanding hinders executing our project because the public would still be wary of GMO based products and conclude they are unsafe. Thus, our education mainly focused on promoting synthetic biology and its application.</p>
                    </p>
+
                    <div class="container-fluid p-0">
                    <p>    From these responses, we could deduce that there is still a large percentage of people who do not fully support or are neutral about gene editing, especially when it comes to gene-edited bacterial drugs. As such, we can conclude that there is still a long way to go before gene-edited pharmaceutical products like CreSolve (our live therapeutic drug) is able to hit the market. However, we are still optimistic that given enough time and education, live therapeutics can become a staple in medical treatments.
+
                         <div class="row no-gutters">
                    </p>
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                             <div class="col-lg ">
                    <div class="container">
+
                              <a href="https://static.igem.org/mediawiki/2021/c/c9/T--NCKU_Tainan--hpgmo.png" target="_blank" style="width:10%"><img src="https://static.igem.org/mediawiki/2021/c/c9/T--NCKU_Tainan--hpgmo.png" alt="" title="" style="width:100%"></a>
                         <div class="row">
+
                                <figcaption class="mt-3"></figcaption>
                             <div class="col-md-4 col-12">
+
                              </div>
                                <figure class="figure-default-100">
+
                        </div>
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/8/81/T--NCKU_Tainan--IHP_graph_7.png" style="width: 125%;">
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              </div>
                                        <img src="https://static.igem.org/mediawiki/2019/8/81/T--NCKU_Tainan--IHP_graph_7.png" alt="survey-1" title="survey-1" style="width: 125%;">
+
                 </section>-->
                                    </a>
+
                                </figure>
+
                                <figcaption class="center"><p><p>Fig. 7. What is your level of support for ‘Genetic Engineering’ or ‘Genetic Modification’?</p></figcaption>
+
                            </div>
+
                            <div class="col-md-4 col-12">
+
                                <figure class="figure-default-100">
+
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/2/2a/T--NCKU_Tainan--IHP_graph_8.png" style="width: 125%;">
+
                                        <img src="https://static.igem.org/mediawiki/2019/2/2a/T--NCKU_Tainan--IHP_graph_8.png" alt="survey-2" title="survey-2" style="width: 125%;">
+
                                    </a>
+
                                </figure>
+
                                <figcaption class="center"><p><p>Fig. 8. What is your level of support for the development of "gene-edited" bacterial drugs?</p></figcaption>
+
                            </div>
+
                            <div class="col-md-4 col-12">
+
                                <figure class="figure-default-100">
+
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/e/e7/T--NCKU_Tainan--IHP_graph_9.png" style="width: 125%;">
+
                                        <img src="https://static.igem.org/mediawiki/2019/e/e7/T--NCKU_Tainan--IHP_graph_9.png" alt="survey-3" title="survey-3" style="width: 125%;">
+
                                    </a>
+
                                </figure>
+
                                <figcaption class="center center-font"><p><p>Fig. 9. Will you agree to use "gene edited" bacterial drugs?</p></figcaption>
+
                            </div>
+
                        </div>
+
                    </div>
+
                 </section>
+
 
                 <!--Survey---4-->
 
                 <!--Survey---4-->
 
                 <section class="margin-bottom-10">
 
                 <section class="margin-bottom-10">
                     <h3 class="center-font margin-top-5"><i>p</i>-Cresol Detector Acceptance</h3>
+
                     <h3 class="center-font margin-top-5">Menbles Acceptance</h3>
 
                     <hr class="hr-half">
 
                     <hr class="hr-half">
                     <p>   Last, we wanted to assess the sample population’s acceptance when it comes to utilizing a <i>p</i>-Cresol Detector. Thus, we established a few questions first to understand the current situation and whether or not there is a need for this detector. 38% have ever done a kidney function test (see Fig.10), but only a mere 9% has ever done a self-paid uremic toxin test (see Fig. 11). However, we cannot know for sure if the reason there is only a small percentage of people doing uremic toxin tests is because of lack of knowledge or lack of need.
+
                     <p>&emsp;&emsp;We explained briefly in the survey about our project and asked their willingness to try out our product. Surprisingly, ⅔ of the respondents answered yes and considered, leaving ⅓ rejecting to try out our product. Furthermore, when asked about the factors that matter most to them in a stress-relieving product, there are three significant factors: benefit, safety, and price. Based on these survey results, we believe our product has potential in the market. </p>
                    </p>
+
                      <div class="container-fluid p-0">
                    <p>    We performed this survey to understand more about what the public wants and needs when it comes to a uremic toxin detector, to further understand CreSense, our blood <i>p</i>-Cresol quantification device’s value in the market. Most are concerned about the accuracy and cost of the device, with 67% only accepting the device if the price-tag is below 50 USD. That being said, we are happy to say that each CreSense test will cost less than $2, which is much lower than the public’s estimation.
+
                         <div class="row no-gutters">
                    </p>
+
                             <div class="col-lg ">
                    <div class="container">
+
                                 <figure class="d-flex flex-column justify-content-center align-items-center px-lg-3">
                         <div class="row margin-bottom-5">
+
                         
                             <div class="col-md-6 col-12">
+
                               
                                 <figure class="figure-default-100 text-center">
+
                                <a href="https://static.igem.org/mediawiki/2021/8/83/T--NCKU_Tainan--surveyresults4.png" target="blank" width="70%">
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/4/4d/T--NCKU_Tainan--IHP_graph_10.png">
+
                                    <img src="https://static.igem.org/mediawiki/2021/8/83/T--NCKU_Tainan--surveyresults4.png" alt="" width="100%">
                                        <img src="https://static.igem.org/mediawiki/2019/4/4d/T--NCKU_Tainan--IHP_graph_10.png" alt="survey-1" title="survey-1">
+
                                </a>
                                    </a>
+
                         
                                </figure>
+
                              </figure>
                                <figcaption class="center"><p><p>Fig. 10. Have you ever did a "Kidney Function Test" (Ex: Creatinine test)?</p></figcaption>
+
 
                             </div>
 
                             </div>
                            <div class="col-md-6 col-12">
+
                        </div>
                                <figure class="figure-default-100">
+
              </div>
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/d/d3/T--NCKU_Tainan--IHP_graph_11.png">
+
                                        <img src="https://static.igem.org/mediawiki/2019/d/d3/T--NCKU_Tainan--IHP_graph_11.png" alt="survey-2" title="survey-2">
+
                                    </a>
+
                                </figure>
+
                                <figcaption class="center"><p><p>Fig. 11. Have you ever did a "self-paid uremic toxin test"?</p></figcaption>
+
                            </div>
+
                        </div>
+
                        <div class="row">
+
                            <div class="col-md-6 col-12">
+
                                <figure class="figure-default-100">
+
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/a/a8/T--NCKU_Tainan--IHP_graph_12.png">
+
                                        <img src="https://static.igem.org/mediawiki/2019/a/a8/T--NCKU_Tainan--IHP_graph_12.png" alt="survey-3" title="survey-3">
+
                                    </a>
+
                                </figure>
+
                                <br>
+
                            <figcaption class="center-flex center-font"><font size="+1">Fig. 12. Which of the following are you concerned about when choosing a "blood uremic toxin detector"? (Multiple choice)</figcaption></font>
+
                            </div>
+
                            <div class="col-md-6 col-12">
+
                                <figure class="figure-default-100">
+
                                    <a target="blank" href="https://static.igem.org/mediawiki/2019/f/f9/T--NCKU_Tainan--IHP_graph_13.png">
+
                                        <img src="https://static.igem.org/mediawiki/2019/f/f9/T--NCKU_Tainan--IHP_graph_13.png" alt="survey-3" title="survey-3">
+
                                    </a>
+
                                </figure>
+
                              <br>
+
                                <figcaption class="center-flex center-font"><font size="+1">Fig. 13. What amount of "self-paid detection fee" can you accept? (Amount in USD)</figcaption></font>
+
                            </div>
+
                        </div>
+
                    </div>
+
 
                 </section>
 
                 </section>
 
             </div>
 
             </div>
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<br></br>
 
<br></br>
  
   <div class="col-md-12 row" style="
+
    <!--Container-->
padding-left: 6em;
+
    
padding-right: 5em !important;margin-bottom: 5em;">
+
<div class="container">
                      
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<div class="col-md-3"><div style="
+
            <div class="face face1">
;
+
                <div class="content">
float: left;
+
                    <img src="https://static.igem.org/mediawiki/2021/2/21/T--NCKU_Tainan--hp_page7.png">
border: 3px solid #698EC3;margin: 0px;padding: 0px;border-radius: 16px; ;"><a href="https://2021.igem.org/Team:NCKU_Tainan/Entretreneurship"><div style="
+
                     <h3>Entrepreneurship</h3>
background-position: center center;
+
                </div>
background-size: cover;
+
            </div>
;
+
            <div class="face face2">
height: 142px !important;
+
                <div class="content">
border-top-left-radius: 10px;
+
                    <p>One step forward bringing MenTAUR into a reality.</p>
border-top-right-radius: 10px;
+
                        <a href="https://2021.igem.org/Team:NCKU_Tainan/Entrepreneurship">Read More</a>
background-image: url(https://static.igem.org/mediawiki/2021/a/ae/T--NCKU_Tainan--FITI_test3.png);"></div><p style="
+
                </div>
padding: 24px;" >Find out what we have done for entretreneurship</p></a>
+
            </div>
 +
        </div>
 +
        <div class="card">
 +
            <div class="face face1">
 +
                <div class="content">
 +
                    <img src="https://static.igem.org/mediawiki/2021/a/a3/T--NCKU_Tainan--hp_page5.png">
 +
                    <h3>Collaboration</h3>
 +
                </div>
 +
            </div>
 +
            <div class="face face2">
 +
                <div class="content">
 +
                    <p>Working together with other iGEM teams across the world.</p>
 +
                        <a href="https://2021.igem.org/Team:NCKU_Tainan/Collaborations">Read More</a>
 +
                </div>
 +
            </div>
 +
        </div>
 +
        <div class="card">
 +
            <div class="face face1">
 +
                <div class="content">
 +
                    <img src="https://static.igem.org/mediawiki/2021/8/80/T--NCKU_Tainan--hp_page6.png">
 +
                    <h3>Communication</h3>
 +
                </div>
 +
            </div>
 +
            <div class="face face2">
 +
                <div class="content">
 +
                    <p>The key to understand the public through communication and education.</p>
 +
                        <a href="https://2021.igem.org/Team:NCKU_Tainan/Communication">Read More</a>
 +
                </div>
 +
            </div>
 +
        </div>
 +
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 +
 
 +
 
 +
  <!--container css-->
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  <style>
 +
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 +
 
 +
    body{
 +
    margin: 0;
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    padding: 0;
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    min-height: 100vh;
 +
    background: #332E2D;
 +
    display: flex;
 +
    justify-content: center;
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}
 +
   
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      .container .card .face.face1 .content h3{
 +
    margin: 10px 0 0;
 +
    padding: 0;
 +
    color: #FFFBF3;
 +
    text-align: center;
 +
    font-size: 1.3em;
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}
 +
   
 +
   
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  .container{
 +
    width: 1000px;
 +
    position: relative;
 +
    display: flex;
 +
    justify-content:space-between;
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 +
   
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}
 +
   
 +
    .container .card{
 +
    position: relative;
 +
    cursor: pointer;
 +
    border-radius:10px;
 +
}
  
</div></div>
+
.container .card .face{
<div class="col-md-3"><div style="
+
    width: 300px;
;
+
    height: 200px;
float: left;
+
    transition: 0.5s;
border: 3px solid #698EC3;margin: 0.01px;padding: 0px;border-radius: 16px; ;"><a href="https://2021.igem.org/Team:NCKU_Tainan/Collaboration"><div style="
+
}
background-position: center center;
+
background-size: cover;
+
;
+
height: 142px !important;
+
border-top-left-radius: 10px;
+
border-top-right-radius: 10px;
+
background-image: url(https://static.igem.org/mediawiki/2021/a/ae/T--NCKU_Tainan--FITI_test3.png);"></div><p style="
+
padding: 24px;">Find out what we have done for collaboration</p><br></a>
+
  
</div></div>
+
.container .card .face.face1{
<div class="col-md-3"><div style="
+
    position: relative;
;
+
    background: #332E2D;
float: left;
+
    display: flex;
border: 3px solid #698EC3;margin: 0.01px;padding: 0px;border-radius: 16px; ;"><a href="https://2021.igem.org/Team:NCKU_Tainan/Entretreneurship"><div style="
+
    justify-content: center;
background-position: center center;  
+
    align-items: center;
background-size: cover;
+
    z-index: 1;
;
+
    transform: translateY(100px);
height: 142px !important;
+
  border-radius:10px;
border-top-left-radius: 10px;
+
}
border-top-right-radius: 10px;
+
background-image: url(https://static.igem.org/mediawiki/2021/a/ae/T--NCKU_Tainan--FITI_test3.png);"></div><p style="
+
padding: 24px;">Find out what we have done for public engagement</p></a>
+
  
</div></div>
+
.container .card:hover .face.face1{
<div class="col-md-3"><div style="
+
    background: #698EC3;
;
+
    transform: translateY(0);
float: left;
+
}
border: 3px solid #698EC3;margin: 0.01px;padding: 0px;border-radius: 16px; ;"><a href="https://2021.igem.org/Team:NCKU_Tainan/Entretreneurship"><div id="btnHomeModel" style="
+
background-position: center center;  
+
background-size: cover;
+
;
+
height: 142px !important;
+
border-top-left-radius: 10px;
+
border-top-right-radius: 10px;
+
background-image: url(https://static.igem.org/mediawiki/2021/a/ae/T--NCKU_Tainan--FITI_test3.png);"></div><p style="
+
padding: 24px;">Find out what we have done for inclusivity</p><br></a>
+
  
</div></div>
+
.container .card .face.face1 .content{
                   
+
    opacity: 0.2;
 
+
    transition: 0.5s;
                    </div>
+
  display: block;
 +
    text-align: center;
 +
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 +
 
 +
.container .card:hover .face.face1 .content{
 +
    opacity: 1;
 +
  display: block;
 +
    text-align: center;
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 +
 
 +
.container .card .face.face1 .content img{
 +
    max-width: 100px;
 +
 
 +
}
  
  
  
 +
.container .card .face.face2{
 +
    position: relative;
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    background: #FFFBF3;
 +
    display: flex;
 +
    justify-content: center;
 +
    align-items: center;
 +
    padding: 20px;
 +
    box-sizing: border-box;
 +
    box-shadow: 0 20px 50px rgba(0, 0, 0, 0.8);
 +
    transform: translateY(-100px);
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    border-radius:10px;
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 +
    transform: translateY(0);
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 +
 +
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 +
    margin: 0;
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 +
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 +
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 +
    display:  inline-block;
 +
    text-decoration: none;
 +
    font-weight: 900;
 +
    color: #332E2D;
 +
    padding: 5px;
 +
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 +
 
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 +
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 +
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 +
   
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Latest revision as of 14:32, 15 December 2021



Overview

  Communicating science to the public is not an easy task; sometimes, we need to adjust how we deliver our research to various audiences. We also need to understand what benefit the audience will receive from the systems and technology we bring. Therefore, Human Practices became an indispensable part of our project, which acts as a bridge between researchers and general audience or even experts in different fields.

  By closely collaborating with professionals and profoundly investigating the potential consumers' demands, we ensure our product development is beneficial to our community. We constructed a framework for our human practice project that can be categorized into two main parts: business promotion and education. We reached out to several experts to optimize our product and constructed our business model while considering intellectual property, laws, and regulations for business promotion. To mature our designs, we turned to doctors, researchers, and experts in product development for advice.

  The educational section was a collective set targeting several audiences to spread information about synthetic biology. We attempted to discover multiple approaches and viable options to promote our products and collect feedback from our audiences.





Expert visits


  Before we are able to get started on developing our idea into a product, we need to make sure that our idea is as close to perfect as possible, and that means tons of research and experiments. But, the real problem with many ideas, and perhaps the reason why many fail to become a success, is a lack of expertise. No matter how much time and effort we put into research, there will always be an expert who knows the topic or even industry much better than we do. So, to help further verify and improve our ideas, we visited several experts in different fields.

Dr. Po-See Chen  5/28

Director, Division of General Psychiatry, National Cheng Kung University Hospital
Professor, Institute of Behavioral Medicine, National Cheng Kung University

  We met with Dr. Po-See Chen online to obtain further knowledge about depression. He provided us with valuable insight and information regarding the characteristics of depression and the relation of depression with the gut. We met him during the early stages of our project, and he gave us a lot of valuable advice regarding the behavior of patients, such as self-diagnosis which is very dangerous among people who suffer from depression. By conducting this meeting, we can understand more regarding the nature of depression to continue with our project. He also gave advice regarding our education activities, encouraging us to better spread awareness regarding depression, which you can find in our education page.

Professor Yu-Cheng Lin

Professor, Department of Engineering Science, National Cheng Kung University

  Our first hardware idea was to detect human stress levels through saliva, we planned to extract cortisol which is the biomarker of stress, by detecting cortisol levels throughout a couple of days, we will be able to determine someone’s depression level. We made several discussions with professor Yu-Cheng Lin due to the fact that he has the real experience of extracting the different substances from saliva and detect the concentration of several substances through the paper-based electrochemical device. We wanted to continue and make this concept a reality, but suddenly covid-19 strikes Taiwan, so we were not able to go into any lab and we finally suspend the idea then search for another alternative.

Professor Chung-Hsien Wu

Professor, Department of Computer Science, National Cheng Kung University

  Due to the fact that covid-19 in Taiwan escalated very quickly, we were thinking to find another way to build something even that we are not present physically. Then, we had an idea to made an artificial intelligence that can automatically detect depression using sound, and because none of our team members is from the Department of computer science we asked for guidance from Prof. Chung-Hsien Wu in developing the artificial intelligence.

Professor Chien-Hsiang Chang

Professor, Department of chemical engineering, National Cheng Kung University

  Before settling with our current procedure of manufacturing Menbels, we wanted to make sure that our procedure and knowledge are sufficient for us to meet the requirements and make our system feasible to work. And professor Chien-Hsiang Chang has experience in making alginate layers to wrap several substances, Prof. Chang also ensures us that our plan is feasible and isn’t very hard to perform.

Enterprise visit


  Just because an idea is good does not always mean it will sell well in the market. Our product may be designed and modified in the laboratory and adjusted to maximize its performance. However, we needed advice from potential stakeholders to ensure our product will meet real-world demands. We need to interact with industries to understand more about the industrial environment and current market situation. So, in order to refine our idea into a product suitable for the market, we visited several enterprises.

Trade Wind Biotech

  Trade Wind Biotech (TWBIO) is a pioneer company based in Taiwan that implements synthetic biology as its core technique. We were allowed to visit their factory and laboratory led by Dr Lance, the CEO of TWBIO. We also invited team CCU_Taiwan to join us on this trip, and both of our teams received a lot of feedback from Dr Lance regarding entrepreneurship and presentation skills.

Chen En Food Product Enterprise Co., Ltd

  Our team was honoured to interview the general manager of Chen En Food Product Enterprise, Mr Vincent, as Chen En is one of the largest bubble suppliers in both local and global markets. Before the online interview session began, we signed a Memorandum of Understanding (MOU) with them. As a giant bubble supplier, they provided advice on preparing our bubble with the engineered bacteria inside. In addition, they also gave us valuable market data to further our business model.

genemont

8D Tea Fresh Kitchen

  We visited a local handmade bubble tea shop in Nantou and their IoT live kitchen to learn more about bubble production and marketing. They also suggested we market our product as chilled ready-to-eat (RTE) food, allowing us to position it in the market correctly. We also witnessed how they made bubbles from scratch and learned of the sterilization and bubble heating process. For more details, please click on the file below!

2021 NCKU iGEM Survey


  Genetically Modified Organisms (GMOs) are becoming more prevalent in our society due to their wide range of potential applications. Although more research has been conducted regarding the safety of GMOs, many still believe that GMOs are not safe, and it remains to be a controversial topic among society.

  To better understand how the public perceives GMOs and mental health issues, we conducted an online survey. Through the survey, we were able to collect hundreds of respondents’ opinions along with their feedback on our project.

Sample Demographics


  73.3% of our respondents were young adults aged between 18-29 years old, education levels between highschool to university.

Understanding


  As we mentioned above, we wanted to collect the public’s views on mental health issues. Therefore, we divided the respondents into those who have suffered from depression and those who have not. For those who have experienced depressive symptoms, we asked more follow-up questions. 54.5% answered that the primary cause of their depression is stress. Apart from this, we also asked about their opinions about the current solution to depression. The answers were relatively evenly distributed, with concerns about side effects, low effectiveness, and price.

Menbles Acceptance


  We explained briefly in the survey about our project and asked their willingness to try out our product. Surprisingly, ⅔ of the respondents answered yes and considered, leaving ⅓ rejecting to try out our product. Furthermore, when asked about the factors that matter most to them in a stress-relieving product, there are three significant factors: benefit, safety, and price. Based on these survey results, we believe our product has potential in the market.



Entrepreneurship

One step forward bringing MenTAUR into a reality.

Read More

Collaboration

Working together with other iGEM teams across the world.

Read More

Communication

The key to understand the public through communication and education.

Read More