Background
Up to 3500 million people have oral problem
47% of adults aged over 30 years have some form of periodontal disease
Yitzu Juan (Talk | contribs) |
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</section> | </section> | ||
<section> | <section> | ||
− | Processed foods | + | Processed foods become softer and cleaner, setting up a perfect storm for caries: less chewing to |
cut the organic film and fewer dietary abrasives to wear away the nooks and crannies in teeth where | cut the organic film and fewer dietary abrasives to wear away the nooks and crannies in teeth where | ||
Plague bacteria take refuge. | Plague bacteria take refuge. | ||
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detecting the number of bacteria in a single dog's mouth. | detecting the number of bacteria in a single dog's mouth. | ||
</p> | </p> | ||
− | <h2> | + | <h2>Inhibition</h2> |
− | <p class="ProjIntro-content">In DenTeeth, antimicrobial peptides are used to | + | <p class="ProjIntro-content">In DenTeeth, antimicrobial peptides are used to inhibit the growth of bacteria. We use antimicrobial peptide LL-37, which activates autophagy and leads to cell death. |
− | + | ||
</p> | </p> | ||
<h2>Reduction of biofilm and odors</h2> | <h2>Reduction of biofilm and odors</h2> | ||
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project, which is able to reduce the formation of biofilms and reduce the odors as well. | project, which is able to reduce the formation of biofilms and reduce the odors as well. | ||
</p> | </p> | ||
− | <h2> | + | <h2>Restoration</h2> |
− | <p class="ProjIntro-content"> | + | <p class="ProjIntro-content">In addition to eliminating the main factor forming oral problems, restoration of teeth and |
− | periodontal are also | + | periodontal are also necessary. |
</p> | </p> | ||
− | <p class="ProjIntro-content">After the | + | <p class="ProjIntro-content">After the number of bacteria is below a certain value, the mechanism of restoration |
will open, several proteins which can repair damaged gingiva or tooth tissue would be expressed. | will open, several proteins which can repair damaged gingiva or tooth tissue would be expressed. | ||
</p> | </p> |
Up to 3500 million people have oral problem
47% of adults aged over 30 years have some form of periodontal disease
The dogs older than three years old
Up to 80% of dogs have some form of periodontal disease
One of our main goals is the development of detection that is based on machine learning. Customize the period of time feeding DenTeeth and improve the effect of DenTeeth by detecting the number of bacteria in a single dog's mouth.
In DenTeeth, antimicrobial peptides are used to inhibit the growth of bacteria. We use antimicrobial peptide LL-37, which activates autophagy and leads to cell death.
Based on previous studies, the bacteria on the teeth surface form biofilms which leads to the formation of tartar. In order to solve this problem, we introduce arginine into our project, which is able to reduce the formation of biofilms and reduce the odors as well.
In addition to eliminating the main factor forming oral problems, restoration of teeth and periodontal are also necessary.
After the number of bacteria is below a certain value, the mechanism of restoration will open, several proteins which can repair damaged gingiva or tooth tissue would be expressed.
Next, our goal is to solve the oral health problem in humans.