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{{NCTU_Formosa/header}} | {{NCTU_Formosa/header}} | ||
<html> | <html> | ||
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− | |||
<body> | <body> | ||
<main> | <main> | ||
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</div> | </div> | ||
<div class="main-content"> | <div class="main-content"> | ||
− | <img src="https://static.igem.org/mediawiki/2021/0/02/T--NCTU_Formosa--next.png" id="nextBottom" /> | + | <img src="https://static.igem.org/mediawiki/2021/0/02/T--NCTU_Formosa--next.png" id="nextBottom" /> |
− | <div class="section | + | <div class="section s2"> |
− | <h1 class="topic" id=" | + | <h1 class="topic" id="topic2">Overview</h1> |
− | <p id="p1"> | + | <!--<p id="p1"> |
− |    | + |   Modeling is calculating the physical phenomenon by using mathematical methods or logical algorithms.<br><br><br>--> |
</p> | </p> | ||
− | + | <p id="p2" > | |
− | + |   Oral cavity is a hotbed for pathogens of periodontal diseases, as the goal of modelling is to simulate the microenvironment incorporated with Denteeth, mainly the overturn of pathogens, and make predictions on their extinction. Therefore, we compute the competing bacterial growing patterns, and the killing effect on pathogens. Also, we propose a renew rate of the final product, considering the biobrick design in DenTeeth, including quorum sensing, target peptide expression. Altogether, the model enables DenTeeth to optimize continually with the help of reinforcement AI. The model consists of two parts: | |
+ | <ol id="list" > | ||
+ | <li><a href="https://2021.igem.org/Team:NCTU_Formosa/Prediction_Model">Prediction Model(Click to this | ||
+ | page)</a></li> | ||
+ | <li><a href="https://2021.igem.org/Team:NCTU_Formosa/Efficiency_Optimization_Model">Efficiency | ||
+ | Optimization Model(Click to this page)</a></li> | ||
+ | </ol> | ||
+ | </p><!-- | ||
+ | <div id="Btn_Open"> | ||
+ | <img class="ReadMore2" style="display: none; " id="img_Open" src="https://static.igem.org/mediawiki/2021/1/15/T--NCTU_Formosa--ellipsis.svg"> | ||
+ | </div> | ||
+ | <div id="Btn_Close"> | ||
+ | <img class="ReadMore2" id="img_Close" src="https://static.igem.org/mediawiki/2021/5/50/T--NCTU_Formosa--close.svg">*/ | ||
+ | </div>--> | ||
+ | <img src="https://static.igem.org/mediawiki/2021/2/26/T--NCTU_Formosa--rainnie_model_flow_chart.png?fbclid=IwAR0BygOOr-lu6uy3B2_jgEBJJL4l8N97nVDCRqj4ETNPZRjBqbU7NAFakiQ" class="images" id=" Growth_PE" alt=" growth curve of E. coli and P.gingivalis"/> | ||
+ | <div class="explanation"><svg class="icon" aria-hidden="true" data-prefix="fas" data-icon="arrow-circle-up" | ||
+ | role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"> | ||
+ | <path fill="currentColor" | ||
+ | d="M8 256C8 119 119 8 256 8s248 111 248 248-111 248-248 248S8 393 8 256zm143.6 28.9l72.4-75.5V392c0 13.3 10.7 24 24 24h16c13.3 0 24-10.7 24-24V209.4l72.4 75.5c9.3 9.7 24.8 9.9 34.3.4l10.9-11c9.4-9.4 9.4-24.6 0-33.9L273 107.7c-9.4-9.4-24.6-9.4-33.9 0L106.3 240.4c-9.4 9.4-9.4 24.6 0 33.9l10.9 11c9.6 9.5 25.1 9.3 34.4-.4z"> | ||
+ | </path> | ||
+ | </svg>The structure of the model</div> | ||
+ | </div> | ||
+ | |||
+ | </div> | ||
<div class="dog-button"> | <div class="dog-button"> | ||
− | < | + | <div class="dog-img" id="img-link1"> |
− | <div class="dog-txt"> | + | <div class="dog-txt">Prediction Model</div> |
− | <img src="https://static.igem.org/mediawiki/2021/3/3c/T--NCTU_Formosa--growth_model_link.svg" alt="dog"> | + | <img style="border-radius: 5% 0 0 0;" src="https://static.igem.org/mediawiki/2021/3/3c/T--NCTU_Formosa--growth_model_link.svg" alt="dog"> |
− | </ | + | </div> |
− | < | + | <div class="dog-img" id="img-link2"> |
− | <div class="dog-txt-c"> | + | <div class="dog-txt-c">Efficiency Optimization Model</div> |
− | <img src="https://static.igem.org/mediawiki/2021/8/8a/T--NCTU_Formosa--quorum_link.svg" title="Edward Jenner" alt="Design"> | + | <img style="border-radius: 0 5% 0 0;" src="https://static.igem.org/mediawiki/2021/8/8a/T--NCTU_Formosa--quorum_link.svg" title="Edward Jenner" alt="Design"> |
− | </ | + | </div> |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
</div> | </div> | ||
− | <div id="tab01" class="tab-inner"> | + | <div id="tab01" class="tab-inner" style="display:block;"> |
− | <p> | + | <h1 class="subtopic">Prediction Model</h1> |
+ | <p> | ||
+ |   The Prediction Model is mainly to analyze the growth of bacteria and the expression of protein and peptide. It can also predict the killing rate and sterilization rate. By this model, we can define the efficiency of DenTeeth. | ||
+ | </p> | ||
+ | <a href="https://2021.igem.org/Team:NCTU_Formosa/Prediction_Model"><img class="ReadMore1" src="https://static.igem.org/mediawiki/2021/2/22/T--NCTU_Formosa--double-chevron.svg"></a> | ||
</div> | </div> | ||
<div id="tab02" class="tab-inner"> | <div id="tab02" class="tab-inner"> | ||
− | < | + | <h1 class="subtopic">Efficiency Optimization Model</h1> |
− | + | <p> | |
− | + |   To optimize the frequency of using DenTeeth and making our model applies to the dogs better. We input the results of the Prediction Mode to the Optimized Frequence Model and find out the best strategy. | |
− | + | </p> | |
+ | <a href="https://2021.igem.org/Team:NCTU_Formosa/Efficiency_Optimization_Model"><img class="ReadMore1" src="https://static.igem.org/mediawiki/2021/2/22/T--NCTU_Formosa--double-chevron.svg"></a> | ||
</div> | </div> | ||
− | <div | + | <div style="position: relative;"> |
− | < | + | <a href="https://2021.igem.org/Team:NCTU_Formosa/Prediction_Model"><img id="NextPage" src="https://static.igem.org/mediawiki/2021/5/55/T--NCTU_Formosa--right-arrow.svg"></a> |
− | + | </div> | |
− | + | ||
− | + | ||
− | </div> | + | |
</div> | </div> | ||
+ | <div id="dark_mode"><span class="material-icons"> | ||
+ | dark_mode | ||
+ | </span>Dark Mode</div> | ||
</main> | </main> | ||
</body> | </body> | ||
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animation: floating 3s ease-in-out infinite; | animation: floating 3s ease-in-out infinite; | ||
cursor: pointer; | cursor: pointer; | ||
+ | } | ||
+ | #NextPage{ | ||
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} | } | ||
@keyframes floating { | @keyframes floating { | ||
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transform: scale(1.2); | transform: scale(1.2); | ||
transition: .3s; | transition: .3s; | ||
+ | cursor: pointer; | ||
} | } | ||
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font-size: 3vw; | font-size: 3vw; | ||
line-height: 48px; | line-height: 48px; | ||
− | padding: 10% 10% 5%; | + | padding: 2% 10% 0; |
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.section p{ | .section p{ | ||
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font-size: 2vw !important; | font-size: 2vw !important; | ||
font-family: 'Noto Sans JP', sans-serif; | font-family: 'Noto Sans JP', sans-serif; | ||
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} | } | ||
.images{ | .images{ | ||
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.dog-button { | .dog-button { | ||
display: flex; | display: flex; | ||
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justify-content: space-between; | justify-content: space-between; | ||
justify-content: center; | justify-content: center; | ||
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.dog-txt{ | .dog-txt{ | ||
position: absolute; | position: absolute; | ||
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.dog-txt-c{ | .dog-txt-c{ | ||
position: absolute; | position: absolute; | ||
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− | left: | + | left: 0%; |
text-align: center; | text-align: center; | ||
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color: whitesmoke; | color: whitesmoke; | ||
margin-left: auto; | margin-left: auto; | ||
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opacity: 0.5; | opacity: 0.5; | ||
transition: 0.3s; | transition: 0.3s; | ||
+ | cursor: pointer; | ||
} | } | ||
.tab-inner{ | .tab-inner{ | ||
− | width: | + | width: 80%; |
− | height: | + | height: 400px; |
− | + | background-color: #1d4eac; | |
− | background-color: # | + | border-radius: 0 0 10px 10px; |
− | border-radius: 10px; | + | |
display: none; | display: none; | ||
+ | position: relative; | ||
+ | margin-left: auto; | ||
+ | margin-right: auto; | ||
+ | } | ||
+ | .ReadMore1{ | ||
+ | position: absolute; | ||
+ | width: 6%; | ||
+ | right: 2%; | ||
+ | bottom: 5%; | ||
+ | } | ||
+ | .op{ | ||
+ | opacity: 0.9; | ||
+ | } | ||
+ | .ReadMore1:hover{ | ||
+ | transform: scale(1.2); | ||
+ | } | ||
+ | .ReadMore2{ | ||
+ | position: absolute; | ||
+ | width: 6%; | ||
+ | right: 50%; | ||
+ | bottom: 5%; | ||
+ | } | ||
+ | #img_Open:hover{ | ||
+ | transform: scale(1.2); | ||
+ | cursor: pointer; | ||
+ | } | ||
+ | #img_Close:hover{ | ||
+ | transform: scale(1.2); | ||
+ | cursor: pointer; | ||
+ | } | ||
+ | #list li a{ | ||
+ | font-size: 2vw !important; | ||
+ | } | ||
+ | #list{ | ||
+ | list-style-image: url("https://static.igem.org/mediawiki/2021/b/bc/T--NCTU_Formosa--list_image.svg"); | ||
+ | font-family: 'Noto Sans JP', sans-serif; | ||
+ | padding-left: 5% !important; | ||
+ | font-size: 2vw !important; | ||
+ | padding-bottom: 5%; | ||
+ | } | ||
+ | .night{ | ||
+ | color: whitesmoke; | ||
+ | background-color: #13102c !important; | ||
+ | } | ||
+ | #dark_mode{ | ||
+ | font-size: 5px; | ||
+ | font-family: 'OtomanopeeOne', sans-serif !important; | ||
+ | } | ||
+ | #dark_mode:hover { | ||
+ | cursor: pointer; | ||
+ | color: RGB(253,172,83); | ||
+ | } | ||
+ | #dark_mode:hover .material-icons{ | ||
+ | cursor: pointer; | ||
+ | color: RGB(253,172,83); | ||
+ | } | ||
+ | .explanation { | ||
+ | font-size: 1.3vw; | ||
+ | text-align: center; | ||
+ | margin: 10px 0 10%; | ||
+ | color: RGB(253, 172, 83); | ||
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+ | .explanation i{ | ||
+ | font-size: 1.3vw; | ||
+ | } | ||
+ | .icon { | ||
+ | width: 1.5vw; | ||
+ | color: RGB(253, 172, 83); | ||
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@media screen and (max-width: 750px){ | @media screen and (max-width: 750px){ | ||
#nextBottom{ | #nextBottom{ | ||
− | width: 10%; | + | display: none; |
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+ | #NextPage { | ||
+ | width: 15%; | ||
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.section p{ | .section p{ | ||
font-size: 5vw !important; | font-size: 5vw !important; | ||
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.section p i{ | .section p i{ | ||
font-size: 5vw !important; | font-size: 5vw !important; | ||
+ | } | ||
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} | } | ||
.images{ | .images{ | ||
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font-size: 3vw; | font-size: 3vw; | ||
} | } | ||
+ | .ReadMore1 { | ||
+ | position: absolute; | ||
+ | width: 13%; | ||
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} | } | ||
</style> | </style> | ||
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}); | }); | ||
− | $("# | + | $("#dark_mode").click( |
− | $("# | + | function(){ |
+ | $("#bodyContent").toggleClass("night"); | ||
+ | $(".main-content").toggleClass("night"); | ||
+ | $(".material-icons").toggleClass("night"); | ||
}); | }); | ||
− | $("#img- | + | |
− | $("# | + | $("#img-link1").click(function(){ |
+ | $("#tab01").slideToggle(); | ||
+ | $(".dog-img:not(#img-link1)").addClass( "op" ); | ||
+ | $(this).removeClass( "op" ); | ||
+ | $("#tab02").hide(); | ||
+ | $("#tab03").hide(); | ||
}); | }); | ||
− | $("#img- | + | $("#img-link2").click(function(){ |
− | $("# | + | $("#tab02").slideToggle(); |
+ | $(".dog-img:not(#img-link2)").addClass( "op" ); | ||
+ | $(this).removeClass( "op" ); | ||
+ | $("#tab03").hide(); | ||
+ | $("#tab01").hide(); | ||
}); | }); | ||
+ | |||
+ | |||
+ | //var display1 =$('#tab01').css('display'); | ||
+ | //var display2 =$('#tab02').css('display'); | ||
+ | //var display3 =$('#tab03').css('display'); | ||
+ | //if(display1 == 'none' && display2 == 'none' && display3 == 'none'){ | ||
+ | // $(".dog-img").removeClass( "op" );}; | ||
+ | |||
+ | $("#img_Open").click(function(){ | ||
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+ | $("#p2").slideUp(); | ||
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+ | $(this).hide(); | ||
+ | $("#img_Open").fadeIn(); | ||
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+ | |||
+ | }); | ||
+ | |||
− | |||
</script> | </script> | ||
+ | |||
</html> | </html> | ||
{{NCTU_Formosa/footer}} | {{NCTU_Formosa/footer}} |
Latest revision as of 15:30, 30 November 2021
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Overview
Oral cavity is a hotbed for pathogens of periodontal diseases, as the goal of modelling is to simulate the microenvironment incorporated with Denteeth, mainly the overturn of pathogens, and make predictions on their extinction. Therefore, we compute the competing bacterial growing patterns, and the killing effect on pathogens. Also, we propose a renew rate of the final product, considering the biobrick design in DenTeeth, including quorum sensing, target peptide expression. Altogether, the model enables DenTeeth to optimize continually with the help of reinforcement AI. The model consists of two parts:
Prediction Model
The Prediction Model is mainly to analyze the growth of bacteria and the expression of protein and peptide. It can also predict the killing rate and sterilization rate. By this model, we can define the efficiency of DenTeeth.