Naval Medical University CHINA
Recruiting: We collected nearly 100 students who were interested in participating in the iGEM competition!
First Training: Email etiquette and Synthetic Biology
Second Training: Analysis of iGEM award conditions
HP Sharing: We read the iGEM integrated HP award conditions and shared HP's best cases.
we participated in the data review and partial compilation of the synthetic biology study manual.
First Presentation: Analysis of Excellent wiki over the years
Best wishes for the New Year! We prepared New Year gifts (cards and team USB flash disks) for each team member.
We participated in the data review and partial compilation of the synthetic biology study manual.
Establish Cooperation with Lanzhou University: We have identified long-term and in-depth cooperation with LZU in HP, experiments and model.
“Virus Police” Seven-school Seminar: we gather teams from China in the past two years with the theme of novel coronavirus diagnosis and treatment to hold a seminar for seven schools, namely “Virus”. During this period, we received specific suggestions on the competition.
Project Manual Production: Complete the production of the project manual, to provide assistance for the follow-up team to carry out publicity and education activities.
Suggestions for the Rural Elderly in the Epidemic: We interviewed Dr. Zhang You, who supported Wuhan last year, to understand the inconvenience of the rural elderly living conditions under the conditions of the domestic epidemic. Then we wrote "Reflections and Suggestions on the Basic Life and Medical Security of The Elderly in Rural under the Epidemic", delivering them to the relevant departments and expecting to be answered.
Confirmed as presentation candidates
Filled in the Check - in forms
Expert Interview: We asked professor Guo Meng to evaluate the overall design of our project. He proposed that the existing IL-6 receptors need to be improved so that in the early stage of novel coronavirus infection, macrophages could initially convert to Kill CAR for an immune response, and in the late stage of infection, they could convert to Silent CAR to avoid further upregulation of inflammatory factors.
Completed CAR Macrophages construction
Collaboration with NUDT-China: We achieved agreement with NUDT-China in the aspects of experimental collaboration, proposed some advice and received feedback so as to revise our project.
Collaboration with High School: We provided technical guidance to four high school teams in China, who also raised questions about the failure of macrophage treatment when the viral load was too high. We used model to verify this problem. At the same time, we asked professor Yin from affiliated hospital to help them solve the problem of experimental model.
SARS-CoV-2 Pseudovirus and Cell Infection Experiments
Analysed inflammatory cytokines released by CAR macrophages
Academic Evaluation: In order to evaluate the application of this therapy in real clinical environment, we interviewed Dr. Du Juan from the Hematology Department of Shanghai Changzheng Hospital since cell therapy is mostly used in the field of hematology at present. She gave us specific suggestions based on treatment cost and patient compliance. At the same time, she popularized the deficiency of current laws and regulations in relevant fields in real scenes, providing guidance for our investigation of laws and regulations in this field.
Industrial Evaluation: In order to explore the development of this therapy in the commercial environment, we investigated cell therapy companies in Shanghai, drafted a business plan based on what we learned, and evaluated the development of the future commercialization of this therapy with Mr. Gao, director of investment Banking Division of Guosen Securities in Shanghai.
We investigated related information of cellular immunotherapy, including policy, business and insurance.
Completed safety form