Team:BUCT/jess

• Home
• Team
  • Team members
  • Attributions
  • Collabrations
• Project
  • Description
  • Engineering Success
  • Results
  • Implementation
  • Contribution
• Dry Lab
  • Model
• Wet Lab
  • Safety
  • Notebook
  • Experiments
• Parts
  • Basic Parts
  • Composite Parts
• Human Practices
  • Integrated Human Practice
  • Communication
  • Education

Obesity has always been a threat to human health. It is estimated that 12.5% of people in the world suffer from obesity.

Studies have shown that obesity can aggravate anxiety while depression and anxiety also fuel obesity. It is called the "depression-obesity circle”.

How about bacteria that can consume fatty acid and generate antidepressants?

Our engineering bacteria are expected to synthesize GABA and 5-HTP from fatty acids and glycerol, which serves the purpose of energy transfer. It may break this circle and alleviate people’s “body shame”.

Then, we use E.coli Nissle 1917 as a chassis with enhanced capacity of β-oxidation of fatty acid, thereby increasing fatty acids consumption from diets to facilitate weight loss, and synthesize GABA and 5-HTP to make us get rid of depression.

To sum up, BUCT hopes to realize a therapy which can treat obesity and make the world happier.

The whole BUCT team would like to thank our sponsors. Especially:

tel:15617867095

address:No.15,Beisanhuan East Road,Beijing,P.R.China. Beijing University of Technology