Team:XJTLU-CHINA

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Overview

Food safety is a leading public health concern related to people's health and quality of life.

Illnesses caused by ingestion of contaminated and toxic food or water are foodborne illnesses.

An estimated 600 million people fell ill after eating contaminated food; US$ 110 billion is lost each year in productivity and medical expenses resulting from unsafe food in low- and middle-income countries.

Global

China

In the period of 2003 to 2017, the recorded information showed 107,000 hospitalizations, and 1,457 deaths because of unsafe food

We found that bacterial pathogen is a significant cause of foodborne disease.

According to comprehensive field research and literatures, there are four main demands in bacterial detection.

Fast, Multiply bacteria detection, Quantitative detection, Visible result

However, conventional detection methods such as Culturing and PCR cannot meet these demands.

Fast

We used phage as the specific probe and cell free system to output signal, The whole progress only cost no more than 6 hours.

Multiply bacteria detection

We could be designed as different probes for different bacterial pathogens.

Quantitative detection

The down-stream cell free system could convert foreign protein released to reported signal. .

Visible result

We used eGFP (enhanced GFP) as reporter gene, which could output visible result.

Find details in pages below

Design

Engineering

Modeling

Hunam Practice

Contact Us

igem@xjtlu.edu.cn

Sponsor