Team:Shanghai Metropolis/Entrepreneurship

Executive Summary & Business Introduction

EV71terminator is a biogenetic technology cooperation located in the Torch Core Building, Pudong district, Shanghai. We are committed to provide prediction and protection for people to avoid Hand-Foot-Mouth Disease (HFMD) infection. We are striving to research and develop a new oral vaccine of EV71 virus, the most virulent strain of HFMD, for markets. EV71terminator have contacted experts in various fields including medical specialists, vaccine experts, etc. We have a strong professional team behind us and private laboratory in ATLATL R&D Center, Shanghai, China to support our research and development. We also enter into partnerships with other companies for mutual benefit. Through our effort, we believe our products will lead us to a more secure and healthy life in the future.

Research Methods

Up to now, because of the target that we want to discover the feasibility and the acceptance of the vaccine for EV71, we have interviewed with professors and residents, HFMD's doctor, and experts in the vaccine industry. After we have interviewed for their opinion about the HFMD, oral vaccines, we believe that oral vaccine will be well-accepted according to the answers of these questions we collected . We also designed questionnaires to understand the state of markets and the acceptance level of public. We put it online and receive the answers of public. The questionnaires included three parts of our project. First, we want to understand whether public have a basic understanding of HFMD; second, we estimate the understanding level of public to HFMD vaccine. These two parts enable us to have a basic realization to the public. Third, we would like to evaluate the receptive rate of public to the HFMD vaccine. The questionnaires move our process forward. Beside the questionnaires, we search the knowledge of HFMD vaccine online and find that the market of HFMD oral vaccine is still vacant, which ensures the market prospect of our product. Last but not least, our laboratory experiments will keep following up, providing the strongest support for what we do now and future.

Market Analysis

SWOT Analysis

Competitor Analysis

  1. SINOVAC Enterovirus Type 71 Vaccine (Vero cell): A new drug under “Category 1 Preventative Biological Products, Rapid onset of the vaccine can be achieved, as well as wide coverage for the population aged 6 to 71 months; a 2-dose inoculation grants at least 5 years of protection. Rapid onset of the vaccine can be achieved, as well as wide coverage for the population aged 6 to 71 months,a 2-dose inoculation grants at least 5 years of protection. So,It has almost monopolized the EV71 vaccine market in China and other parts of Asia. It has been on the market for 6 years since 2016, with mature technology and stable price. Price:penicillin bottle:168 yuan each and Prefi lled type:188 yuan each

  2. Enterovirus Type 71 Vaccine, Inactivated(Human Diploid cell)form Institute of Medical Biology, Chinese Academy of Medical Sciences. Chinese have been the most receptive. The price is the same as sinovac's vaccine.

Execution

4P Analysis

Product

Our product is an oral vaccine against EV71 Hand-Foot-and-Mouth Disease. EV71 oral subunit vaccine uses one of the immunological parts of EV71, VP1, to trigger off immune response in both humor and GI tract and prepare specific antibodies and memory cells for future virus invasion. Before our team created it, the oral version of EV71 vaccine had never been appeared. The vaccine we developed has plenty of advantages. For example, our vaccine is a kind of subunit vaccine, so it is much safer than the attenuated vaccines on the market, and it has a wider range and a durable effect, and also it is less demanding to carry and store. In addition, since HFMD is more common among infants and young children, an oral vaccine can prevent children from being afraid of injections.

Price

We are the first team to develop the EV71 oral vaccine, it is unique in the market today. Since it is an oral vaccine, the cost for production can be largely slashed for the disuse of needles, labors, and other costs happened during storage and transportation process. Therefore, we would set the price reasonably, which lower the price of the vaccine, leaving benefits in our customers. However, the research and development costs in the early stage will need to be apportioned, the pricing will certainly not be low, but compared with our competitors, our prices are definitely lower. 

Place

Our marketing was mainly located in a park next to a busy community in Shanghai. We also launched our own products on the network platform and social software, and have special students to manage and operate them. In addition, we also held publicity activities in the cultural activities center to educate more people about relevant knowledge and preventive measures, and the most important thing is that we have our own research and development laboratory. All of these can provide more opportunities for our products.

Promotion

At the aim of expanding the influence of Enterovirus 71 Oral Vaccine, our team set up our WeChat official Account named EV71terminator, on which the process and progress of lab, as well as field research are uploaded and shown to the public, so that target consumers and stakeholders are able to keep pace with the R&D of the oral vaccine. Besides, in order to evoke people’s awareness of the prevention of the Hand-Foot-and-Mouth Disease, we also hold offline science popularization activities at a local cultural activities center, from which people have a prolong understanding of the threat of the HFMD, particularly those who have children, and will attach greater significance and attention to our products. Moreover, we conducted field research at a business center and interviewed virology authority. We also organized a charity bazaar, selling relative products, such as umbrellas, facial masks and tissue, on which the logo of our company is printed. Practices mentioned above advertised Enterovirus &1 oral vaccine effectively.

Evaluation

As a research and development team of oral vaccine for HFMD prevention, EV71terminator mainly targets young children, with a small number of adults. Admittedly, the future of oral vaccines is fraught with uncertainty and many bioscience research unknowns, such as the control of vaccine effectiveness and technical questions about the timing and process of development. Among them, the development of EV71 oral vaccine is a long and complex process, requiring a large investment of time and technology, manpower and equipment will need to be considered. In the future, as the vaccine market continues to expand, the competitiveness of similar drugs is also under consideration.

But at the same time, EV71 oral vaccine development will have the following benefits:

  1. The forefront of vaccine development on the market; At present, there are not many oral vaccines on the market, and the audience is basically infants and young children. With the increase of recognition, it will be adopted by more people of this type. It covers a large population and is particularly suitable for infants because mucosal immunity is not affected by age-related dysfunction. In the future can occupy a certain market stability.

  2. Compared with other types of vaccines in the market, oral vaccines have certain advantages in preservation; No additional special preservation techniques, such as cryopreservation of injectable vaccines, are required.

  3. Saving resources on the cost of medical personnel; The oral vaccine saves the steps of injection compared to the traditional vaccine. This also means that no more health care needs to be paid to manually inject the vaccine.

Conclusion

From the perspective of social situation, the world's birth rate is increasing every year, which means that the number of children is increasing, and the probability of Hand-Foot-and-Mouth Disease will also increase. Obviously, our oral vaccine program will bring benefits to countless families: oral vaccine not only ensures the health of children, but also ensures that every family can live a happy life. Oral vaccine is a project with good development prospects and great returns. Moreover, it can also bring great social welfare and promote social stability and development.

Reference

  1. http://www.sinovac.com.cn/

  2. https://wenku.baidu.com/view/798630d28762caaedd33d466.html

  3. https://baike.baidu.com/pic/SWOT%E5%88%86%E6%9E%90%E6%B3%95/150223/1/d788d43f8794a4c2d954f9f80cf41bd5ac6e39e9?fr=lemma&ct=single#aid=1&pic=d788d43f8794a4c2d954f9f80cf41bd5ac6e39e9