Difference between revisions of "Team:Stockholm"

 
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<!-- # TODO: #6 Fix table caption font--><!-- # TODO: #7 Fix citations links font size--><html lang="en"><head><meta charset="utf-8"/><meta content="width=device-width,initial-scale=1" name="viewport"/><title>iGEM Stockholm</title><link href="https://2021.igem.org/Template:Stockholm/css/indexCSS?action=raw&amp;ctype=text/css" rel="stylesheet"/></head><body><!-- # TODO: #6 Fix table caption font--><!-- # TODO: #7 Fix citations links font size--><nav class="navbar navbar-expand-xl fixed-top"><div class="container d-flex justify-content-between"><a class="navbar-brand d-lg-inline-block" href="https://2021.igem.org/Team:Stockholm"></a><button aria-controls="navbarNav" aria-expanded="false" aria-label="Toggle navigation" class="navbar-toggler" data-target="#navbarNav" data-toggle="collapse" type="button"><span class="navbar-toggler-icon"></span></button><div class="collapse navbar-collapse" id="navbarNav"><ul class="navbar-nav ml-auto"><li class="nav-item dropdown"><a aria-expanded="false" aria-haspopup="true" class="nav-link dropdown-toggle" data-toggle="dropdown" href="#" id="navbarTeamDropdown" role="button">Team</a><div aria-labelledby="navbarTeamDropdown" class="dropdown-menu"><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Team">Team</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Attributions">Attributions</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Collaborations">Collaborations</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Partnership">Partnership</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Inclusivity">Inclusivity</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Sponsors">Sponsors</a></div></li><li class="nav-item dropdown"><a aria-expanded="false" aria-haspopup="true" class="nav-link dropdown-toggle" data-toggle="dropdown" href="#" id="navbarProjectDropdown" role="button">Project</a><div aria-labelledby="navbarProjectDropdown" class="dropdown-menu"><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Description">Description</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Contribution">Contribution</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Engineering">Engineering</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Experiments">Experiments</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Notebook">Notebook</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Proof_Of_Concept">Proof Of Concept</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Results">Results</a></div></li><li class="nav-item"><a class="nav-link" href="https://2021.igem.org/Team:Stockholm/Model">Model</a></li><li class="nav-item dropdown"><a aria-expanded="false" aria-haspopup="true" class="nav-link dropdown-toggle" data-toggle="dropdown" href="#" id="navbarHuman PracticesDropdown" role="button">Human Practices</a><div aria-labelledby="navbarHuman PracticesDropdown" class="dropdown-menu"><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Human_Practices">Human Practices</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Implementation">Implementation</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Entrepreneurship">Entrepreneurship</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Communication">Communication</a><a class="dropdown-item" href="https://2021.igem.org/Team:Stockholm/Education">Education</a></div></li><li class="nav-item"><a class="nav-link" href="https://2021.igem.org/Team:Stockholm/Safety">Safety</a></li></ul></div><div class="d-flex" id="themeSwitchWrapper"><i class="far fa-sun"></i><div id="themeSwitch"><label class="switch" for="themeSwitchInput"><input id="themeSwitchInput" type="checkbox"/><span class="slider round"></span></label></div><i class="far fa-moon"></i></div></div></nav><header class="d-flex justify-content-center align-items-center"><div class="container"><div class="jumbotron"><center><h1>iGEM Stockholm 2021</h1><img src="https://static.igem.org/mediawiki/2021/5/5e/T--Stockholm--img--transparentMIKROSKINsmall2.png"/><h4>The reason we created MIKROSKIN, was to begin a journey for more personalized, cheaper, and accessible health and skin care, to break the stigma of skin problems, and be a part of creating a better world using synthetic biology.</h4><h4>MIKROSKIN was awarded a gold medal, following in a long tradition of iGEM Stockholm.</h4></center><br/><div class="video_wrapper"><center><iframe allowfullscreen="" frameborder="0" height="315" sandbox="allow-same-origin allow-scripts allow-popups" src="https://video.igem.org/videos/embed/85edf26c-7023-4d30-813f-6d06792453da" title="Stockholm: MIKROSKIN (2021) - Project Promotion [English]" width="560"></iframe><p></p><p>If the above video doesn't work for you, feel free to watch our promotion video on MIKROSKIN <a href="https://video.igem.org/w/hxds15EBKjmSTWgZYuMkP1">here!</a></p><iframe allowfullscreen="" frameborder="0" height="315" sandbox="allow-same-origin allow-scripts allow-popups" src="https://video.igem.org/videos/embed/90fc0c90-c0da-4194-931f-cca549f3a77a" title="Stockholm: Mikroskin: an aptamer-based biosensor for the detection of skin micro... (2021) - Team Presentation [English]" width="560"></iframe><p>If the above video doesn't work for you, feel free to watch our presentation video on MIKROSKIN <a href="https://video.igem.org/w/iUoK6c5Yv6sCwkDdEgnARy">here!</a></p></center><p class="lead"></p><hr class="my-4"/><a class="btn btn-primary btn-lg" href="https://2021.igem.org/Team:Stockholm/Description" role="button">Read more</a></div></div></div></header><article><p></p><div class="container"><p></p><figure style=""><img alt="" class="frontimage" src="https://static.igem.org/mediawiki/2021/0/0b/T--Stockholm--homepagefigure1.jpg" style="float: right; padding-left: 40px;"/></figure><h3>The Problem:<p>The skin is our largest organ. Unfortunately for one third of the population, their skin is affected by skin disease (1). This not only negatively influences their physical but for many also decreases their mental health (2). Understanding the cause and mechanism of a disease is important to design an effective treatment plan, but also to improve self-awareness.</p></h3><br/><p></p><figure><img alt="" class="frontimage" src="https://static.igem.org/mediawiki/2021/e/e4/T--Stockholm--homepagefigure2.jpg" style="float: left; padding-right: 40px; margin-top: 45px; margin-bottom: 45px"/></figure><br/><h3>Our Thought Process:<p>The skin microbiota consists of microorganisms like bacteria, fungi and archaea that live on the skin. Having a healthy microbiota means having a balanced proportion of the different bacteria. Dysbiosis is a change in the bacterial proportion that possibly can lead to disease. With the recent leaps in gut microbiota research and motivation within the team we had two questions that we could not let go:</p><li>What if we could go to the root of the cause of skin problems?</li><li>What if our skin microbiota could be linked to skin diseases?</li></h3><br/><figure><img alt="" class="frontimage" padding-right="100px" src="https://static.igem.org/mediawiki/2021/1/10/T--Stockholm--homepagefigure3.jpg" style="float: right; padding-left: 40px; margin-top: 70px"/></figure><br/><h3>Our Project:<p>We aimed to develop an aptamer-based biosensor for detecting skin microbiota dysbiosis.</p><p>This biosensor would be a quick and inexpensive test that enables the detection and quantification of various strains of bacteria present on the skin, without the need for DNA sequencing. By using this tool we want to pave the way for personalised treatment of skin problems and reduce antibiotic usage.</p><p>Our test was aimed for acne vulgaris, the official name for the common form of the disease acne. In this wiki, this will be continuously referred to as acne.</p><p></p></h3><br/><div class="row"><div class="col"><div class="card" style="width: 18rem;"><div class="card-img-top"><img src="https://static.igem.org/mediawiki/2021/d/d7/T--Stockholm--img--amilGFP-protA-BioBrick-Map.png"/></div><div class="card-body"><h5 class="card-title">Experiments</h5><p class="card-text">Want to learn more about our project and the nitty-gritty scientific details?</p><a class="btn btn-primary" href="https://2021.igem.org/Team:Stockholm/Experiments">Read more</a></div></div></div><div class="col"><div class="card" style="width: 18rem;"><div class="card-img-top"><img src="https://static.igem.org/mediawiki/2021/a/a5/T--Stockholm--img--aptamer_protein_seat.png"/></div><div class="card-body"><h5 class="card-title">Model</h5><p class="card-text">Our dry-lab has done a fantastic job working on the model showing our project for you to visualise here!</p><a class="btn btn-primary" href="https://2021.igem.org/Team:Stockholm/Model">Read More</a></div></div></div><div class="col"><div class="card" style="width: 18rem;"><div class="card-img-top"><img src="https://static.igem.org/mediawiki/2021/4/46/T--Stockholm--img--Labcoatproject222.jpg"/></div><div class="card-body"><h5 class="card-title">Human Practices</h5><p class="card-text">Despite the pandemic, we worked tireless to connect with the community and organise safe events for people to get to know our team and work, and have some fun!</p><a class="btn btn-primary" href="https://2021.igem.org/Team:Stockholm/Human_Practices">Read more</a></div></div></div><br/></div><div class="jumbotron"><h3>References<p>1. Flohr C, Hay R. Putting the burden of skin diseases on the global map. British Journal of Dermatology. 2021 ; 184 (2): 189 - 190.</p><p>2. Schuster B, Ziehfreund S, Albrecht H, Biedermann T, Peifer C et al. Happiness in dermatology: a holistic evaluation of the mental burdern of skin diseases. Journal of the European Academy of Dermatology and Venerology. 2020 ; 34 (6): 1331 - 1339</p></h3></div></div></article><footer><div class="container"><a class="fafa" href="https://www.facebook.com/igemstockholm/" target="_blank"><i class="fab fa-facebook" style="font-size:60px;"></i></a><a class="fafa" href="https://www.instagram.com/igemstockholm" target="_blank"><i class="fab fa-instagram" style="font-size:60px;"></i></a><a class="fafa" href="https://www.linkedin.com/company/igemstockholm" target="_blank"><i class="fab fa-linkedin" style="font-size:60px;"></i></a><a class="fafa" href="https://www.youtube.com/channel/UCh_a6JvWdh6N_i5tYFFcpyw" target="_blank"><i class="fab fa-youtube" style="font-size:60px;"></i></a><a class="fafa" href="mailto: igem.sthlm@gmail.com" target="_blank"><i class="fas fa-envelope" style="font-size:60px;"></i></a></div><br/><div class="container"><a class="uni-logo" href="https://ki.se" target="_blank"><img src="https://static.igem.org/mediawiki/2021/b/bb/T--Stockholm--img--ki-whiteback-modified.png" style="width:100px;height:100px;"/></a><a class="uni-logo" href="https://kth.se" target="_blank"><img src="https://static.igem.org/mediawiki/2021/e/e2/T--Stockholm--img--kthwhite-modified.png" style="width:100px;height:100px;"/></a><a class="uni-logo" href="https://su.se" target="_blank"><img src="https://static.igem.org/mediawiki/2021/d/da/T--Stockholm--img--stockholmuni-modified.png" style="width:100px;height:100px;"/></a></div><br/><div class="container"><p>Sample template built using the iGEM Wiki Starter Pack by BITS Goa.</p><p>Code released under the MIT license.</p><p>Based on <a href="https://getbootstrap.com">Bootstrap</a> and themes <a href="https://bootswatch.com/flatly/">Flatly</a> and <a href="https://bootswatch.com/darkly/">Darkly</a> from <a href="https://bootswatch.com/">Bootswatch</a>.</p><p>Some content from the <a href="https://2020.igem.org/Team:Example">iGEM Example Wiki</a>. Images from <a href="https://unsplash.com">Unsplash</a>. Web fonts from <a href="https://fonts.google.com">Google</a>.</p></div></footer><script src="https://2021.igem.org/Template:Stockholm/index-bundleJS?action=raw&amp;ctype=text/javascript"></script></body></html>
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<h1> Welcome to iGEM 2021! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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hello hello test</p>
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<p> Please read the following pages:</p>
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<li> <a href="https://2021.igem.org/Competition">Competition Hub</a> </li>
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<li> <a href="https://2021.igem.org/Competition/Deliverables/Wiki">Wiki Requirements page</a></li>
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<li> <a href="https://2021.igem.org/Resources/Template_Documentation">Template documentation</a></li>
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<h3> Styling your wiki </h3>
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
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<p> You must upload any pictures and files to the iGEM 2021 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. </p>
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<p>When you upload, set the "Destination Filename" to <b> T--YourOfficialTeamName--NameOfFile.jpg</b>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2021.igem.org/Judging/Pages_for_Awards">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and how you plan to do this.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2021.igem.org/Calendar">iGEM 2021 calendar</a> </li>
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<li> <a href="https://2019.igem.org/Team:Vilnius-Lithuania"> 2019 Vilnius Lithuania</a> </li>
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<li> <a href="https://2019.igem.org/Team:NUS_Singapore">2019 NUS Singapore</a> </li>
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<li> <a href="https://2019.igem.org/Team:Lambert_GA">2019 Lambert GA</a> </li>
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<li> <a href="https://2020.igem.org/Team:Waterloo"> 2020 Waterloo</a></li>
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<li> <a href="https://2020.igem.org/Team:TUDelft">2020 TUDelft</a></li>
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<li> <a href="https://2020.igem.org/Team:XMU-China"> 2020 XMU China </a></li>
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<li> <a href="https://2020.igem.org/Team:TAS_Taipei"> 2020 TAS Taipei </a></li>
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Latest revision as of 01:08, 17 December 2021

iGEM Stockholm

iGEM Stockholm 2021

The reason we created MIKROSKIN, was to begin a journey for more personalized, cheaper, and accessible health and skin care, to break the stigma of skin problems, and be a part of creating a better world using synthetic biology.

MIKROSKIN was awarded a gold medal, following in a long tradition of iGEM Stockholm.


If the above video doesn't work for you, feel free to watch our promotion video on MIKROSKIN here!

If the above video doesn't work for you, feel free to watch our presentation video on MIKROSKIN here!


Read more

The Problem:

The skin is our largest organ. Unfortunately for one third of the population, their skin is affected by skin disease (1). This not only negatively influences their physical but for many also decreases their mental health (2). Understanding the cause and mechanism of a disease is important to design an effective treatment plan, but also to improve self-awareness.



Our Thought Process:

The skin microbiota consists of microorganisms like bacteria, fungi and archaea that live on the skin. Having a healthy microbiota means having a balanced proportion of the different bacteria. Dysbiosis is a change in the bacterial proportion that possibly can lead to disease. With the recent leaps in gut microbiota research and motivation within the team we had two questions that we could not let go:

  • What if we could go to the root of the cause of skin problems?
  • What if our skin microbiota could be linked to skin diseases?


  • Our Project:

    We aimed to develop an aptamer-based biosensor for detecting skin microbiota dysbiosis.

    This biosensor would be a quick and inexpensive test that enables the detection and quantification of various strains of bacteria present on the skin, without the need for DNA sequencing. By using this tool we want to pave the way for personalised treatment of skin problems and reduce antibiotic usage.

    Our test was aimed for acne vulgaris, the official name for the common form of the disease acne. In this wiki, this will be continuously referred to as acne.


    Experiments

    Want to learn more about our project and the nitty-gritty scientific details?

    Read more
    Model

    Our dry-lab has done a fantastic job working on the model showing our project for you to visualise here!

    Read More
    Human Practices

    Despite the pandemic, we worked tireless to connect with the community and organise safe events for people to get to know our team and work, and have some fun!

    Read more

    References

    1. Flohr C, Hay R. Putting the burden of skin diseases on the global map. British Journal of Dermatology. 2021 ; 184 (2): 189 - 190.

    2. Schuster B, Ziehfreund S, Albrecht H, Biedermann T, Peifer C et al. Happiness in dermatology: a holistic evaluation of the mental burdern of skin diseases. Journal of the European Academy of Dermatology and Venerology. 2020 ; 34 (6): 1331 - 1339