Difference between revisions of "Team:IISER-Tirupati India/Human Practices"
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Revision as of 11:47, 18 October 2021
OviCloak, a proposed synthetic biology alternative to existing contraceptives, demands thoughtfulness about whether it is responsible and good for the world. Through our human practices, we tried to achieve this through :
- Reflection
- Responsibility
- Responsiveness
Solving real-world problems not only involves creating solutions but creating effective solutions? .Assessment of goodness begins from the creator’s mind, i.e. reflecting upon our own project throughout.
Our team initiated thoughtfulness from the brainstorming sessions in which the problems we wished to address spanned from poverty to plastic pollution. We came up with solutions using synthetic biology to tackle these problems. However, we also verified if our proposed synthetic biology methods are better than the existing solutions/proposed solutions to these problems.
We understood the potential and need of OviCloak from our reflection and background research. (See Description ).
The analysis section of The iGEMers Guide to the Future helped us contemplate the values that we want to embed for the potential users of OviCloak through the stakeholder/value matrix. Health (Safety), Environmental Safety, Autonomy/individual choice are values we wish to embed and as well as fulfilled by OviCloak.
OviCloak being a non-hormonal contraceptive has least to no side effects to the users, thus ensures (Health) Safety.This also ensures no effects like sex reveral caused by hormonal contraceptives are brought in by OviCloak and also,since it fits into the Long Acting Reversible Contraceptive (LARC) spectrum it minimizing carbonprints.Thus,as a green contraceptive is , ensures Environmental Safety. By mitigating chances of Genetically Engineered release by Kill switch, ensures Biosafety. In short, Ovicloak fulfills the value, Safety.
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Integrated Human Practices
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References
- Grazon, C., Baer, R. C., Kuzmanović, U., Nguyen, T., Chen, M., Zamani, M., ... & Galagan, J. E. (2020). A progesterone biosensor derived from microbial screening. Nature communications, 11(1), 1-10
- Burkart, A. D., Xiong, B., Baibakov, B., Jiménez-Movilla, M., & Dean, J. (2012). Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy. The Journal of cell biology, 197(1), 37-44.
- Brantl, S., & Müller, P. (2019). Toxin⁻Antitoxin Systems in Bacillus subtilis. Toxins, 11(5), 262. https://doi.org/10.3390/toxins11050262
- Patiño, R., Bolamba, D., Thomas, P., & Kumakura, N. (2005). Effects of external pH on hormonally regulated ovarian follicle maturation and ovulation in Atlantic croaker.General and comparative endocrinology, 141(2), 126–134. https://doi.org/10.1016/j.ygcen.2004.12.006
- Shi, D., Komatsu, K., Hirao, M., Toyooka, Y., Koyama, H., Tissir, F., ... & Fujimori, T. (2014). Celsr1 is required for the generation of polarity at multiple levels of the mouse oviduct. Development, 141(23), 4558-4568.
- https://live.flatland.agency/12290417/rathenau-igem/
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