Team:BIT/Supportive Structure
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Supportive Structure
Abstract
[Objective]In order to ensure the normal operation of each independent module and between each
module, we designed the following structure to integrate the SlipChip, fluorescence detection
part, temperature control part and related control circuits.
[Methods] Use 3D modeling software to design the shell, and use 3D printing technology to
process and manufacture the shell. In view of the different functions and nature requirements of
each part, different materials are selected for manufacturing. The whole shell of the instrument
is made of photosensitive resin, and the platform that carries the SlipChip and the temperature
control part is made of high-temperature nylon for the consideration of reaction temperature.
[Results] Assemble the various parts of the instrument. After testing, the overall housing of
the instrument has good mechanical properties and can meet the function of supporting the main
module. The relative position of the internal structure is designed reasonably, and there is no
interference problem. It can satisfy the relative position and mechanical property requirements
of the functions of sliding chip, electric sliding rod, optical part, temperature control part,
radiator fan and circuit board. After assembly of the sliding cover, the device has been tested
for good shading performance, which can prevent ambient light from affecting the accuracy of the
fluorescence detection module. The nylon material used for the platform carrying the SlipChip
and the temperature control part has good heat resistance and can meet the temperature
requirements for biological reactions.
Fig1. Physical map of the whole machine
Video1. Whole machine display video
Material Introduction
The whole shell and most parts of the instrument are made of photosensitive resin. As a 3D
printing material, photosensitive resin has the advantages of simple structure, stable work,
high molding accuracy, high production efficiency, and cost saving.
The platform for carrying the SlipChip and the temperature control part is made of nylon. Nylon
is wear-resistant, tough, and strong. It can be reinforced with carbon fiber or glass fiber, so
that lightweight parts have excellent mechanical properties. Because it is necessary to perform
an amplification reaction of up to 67°C on this part of the structure, nylon with good heat
resistance was finally selected as the material for the 3D printing of the loading platform.
Parts introduction
Slipchip loading platform
As shown in Fig4, we designed this structure to integrate the SlipChip with the heating module.
As shown in Fig5, we designed the structure to fix the structure in Fig4 to the shell. In order
to reduce the material strength requirements for supporting the structure in Fig4, we designed
two vertical struts, one horizontal strut, and a horizontal plug-in support plate to support the
structure in Fig4. And a pull-out card slot is designed in the middle position under Fig5 to fix
the electric push rod used for the self-driving of the SlipChip. In the structure of Fig5, a
heat dissipation hole is left on the right side wall to dissipate the heat during cooling. The
SlipChip, heating and cooling module, and electric push rod are installed as shown in Fig6.
When designing the structure in Fig4, we combined the physical structure of the SlipChip,
leaving holes for the screws and nuts at the four corners, and designed bumps to ensure the chip
is fixed when sliding.
Video2. Loading platform display video
Fig4. Slipchip loading platfrom
Fig5.Instrument shell
Fig6.Finish installation
Connecting ring
Scanning optical inspection requires an electric sliding rod to push the optical components. For
this reason, we designed a connecting ring as shown in Fig.7 to meet the requirements of
scanning optical inspection and realize multi-channel fast switching inspection. The effect
after connection is shown in Fig8.
Fig. 7 Connecting ring
Fig. 8 Connected model diagram
Instrument housing design
Like Fig9 and Fig10, in order to facilitate the internal assembly and sample addition of the
reaction, we designed a spliced upper cover, a front cover that slides up and down, and a
pull-out design of the reaction body.
Fig9.Splice design
Fig10.Splicing complete
Instrument assembly and use
Instrument Assembly
Inside the instrument, as shown in Fig11, the right side is the main part of the reaction,
including sliding chip, electric sliding rod, optical part and temperature control part. On the
right side, from bottom to top, there are micro electric push rods controlling the movement of
sliding chip, load-bearing structure of sliding chip, sliding chip, optical component,
connecting ring and the miniature electric push rod fluorescence detection circuit board that
controls the movement of the optical component On the left side are the radiator fan, the
temperature control circuit board and the micro electric push rod control circuit board.
Video3. Whole machine display video
Install the upper cover and the front cover in turn, as shown in Fig12 and Fig13 respectively.
Instrument Use
The user only needs to follow the operation prompts of the WeChat applet to add samples to
complete the use of the instrument. As shown in Fig14, pull out the main part of the reaction to
load the reagents.
Fig14. Repeated reagent dosing