Team:BIT/Communication

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Education & Communication
In this part, team BIT carry out Education & Communication activities this year based on the principles of "online and offline ", "interview and return visit", and "educate and being educated". In this part, we believe that while communicating with the public and conducting popular science publicity, we should also communicate with experts, scholars and other iGEM teams. Communicating with experts and scholars will help us improve our knowledge level so we can be able to conduct popular science publicity more professionally; communicating with other teams will help us exchange experience in popular science publicity so we can assist each other in conducting popular science together, which can play a better role Effect.
Therefore, in the Education & Communication section, we have not only carried out traditional popular science publicity measures such as conducting science popularization lectures for college and middle school students, conducting popular science publicity to the public and network publicity such as video publicity at Bilibili and public science publicity through WeChat public account. We have also worked hard to improve our professional knowledge and participated in activities such as space training courses, medical-industrial integration forums and visits to the Bluepha. Not only that, we are also actively getting in touch with other iGEM teams to jointly carry out popular science publicity.
MODULE 1
Offline iGEM Lecture
2021.9.23&2021.9.30
Offline salon (For college students)
In this offline salon, we introduced the meaning and pursuit of iGEM competition, our team BIT and our projects to the students. By introducing our projects and promoting iGEM, we analyzed the advantages of participating in the iGEM competition from the perspective of individual participation: systematically learned synthetic biology, promoted by learning different skills. Also we harvest strong friendships. We tell our story in iGEM from the most simple point of view, so that more students can understand iGEM and how they can grow in iGEM. In the salon, we answer the questions of the participants about iGEM and expand the public influence of iGEM.
The salon aroused students’ interest in synthetic biology and also opened the door of iGEM for everyone. After the salon, some students also stayed alone to learn about iGEM in detail with us. The students showed their interest in synthetic biology and our team. We believe they will become iGEMer in the future.

Fig.1：The first salon photo

After our first lecture, many students hope that we will carry out more related lectures. Therefore, we added a second lecture on the second day to popularize colorectal cancer-related knowledge. The students learned about the main causes of colorectal cancer, basic detection methods, Preventive measures and main detection methods. During the interaction during the lecture, we learned that some of the family members of classmates or friends`families have had colorectal cancer patients. We hope that the lecture can help everyone learn more about colorectal cancer and how to prevent the occurrence of colorectal cancer.

Fig.2：audience

In this lecture, we also further talked about the introduction of colorectal cancer POCT detection by the team BIT. The advanced technologies such as isothermal nucleic acid amplification and CRISPER gene editing of synthetic biology integrated in the project. It gave the students a deeper understanding of iGEM and our team. The interaction with the students aroused mutual discussion and at the same time The students are curious about the new subject of synthetic biology.

Fig.3：Interact with the audience

On the premise that the first two lectures were effective, we invited four iGEM teams to jointly hold the third joint science lecture. The other three participating teams were BIT-China, iBowu-China and BUCT-China. The four teams used online and offline methods to explain why ethics is so important; artificial meat-the ethical issues of the future popularization of food science; ethical controversies of artificial life; ethical issues in organ transplantation. In this lecture, we discussed ethical issues together, which is very helpful to strengthen our understanding of basic experimental safety and experimental ethics codes in the process of experimental design. At the same time, the students who participated are very helpful to our lectures. Interests, raised a series of questions such as "What will the taste of artificial meat be like?", "The ethical issues involved in animal organ transplantation in organ transplantation", etc. The discussion process is a collision of various wonderful ideas. Students can also have a deeper understanding of the content of our lectures.

Fig.4：Team BIT-China，iBowu-China and BUCT-China

Fig.5： Team BIT

MODULE 2
Into the middle school
Offline lecture(For middle school students) 2021.10.8
In order to push the knowledge and charm of iGEM into middle school education, we went to Beijing Yucai Middle School. In the lecture, our team leader Liu Zhoumi introduced iGEM and synthetic biology to middle school students who are full of unknown but full of imagination about iGEM. He all introduced our team and our project, so that students have a deeper understanding of iGEM. During the lecture, he also linked synthetic biology with the interesting project of iGEM to arouse students' divergent thinking and helped them better understand synthetic biology.

Fig.6：Offline lecture

During the interaction, the students asked us many interesting questions such as "Did Spider-Man undergo genetic engineering changes?", "Then we can resurrect people from the dead through synthetic biology" and so on. These little questions seem "strange" but in fact it is the children's yearning for the unknown world. Their thinking is very valuable. Under our science popularization, the students showed their curiosity and interest in iGEM and synthetic biology. We believe some of them will become iGEMer when they become high school students.
MODULE 3
Online Popular Science Propaganda
In China, the WeChat public account is a widely used publicity tool by the media and enterprises. The production and forwarding of its articles can be used as a tool to increase publicity. Every day our articles can be sent to fans who follow the account to promote the project and iGEM science popularization. In the past few months, Team BIT's WeChat public account has published about 18 articles, and obtained almost 10K+ page visits. The content of the article includes team promotion, project introduction, popularization of synthetic biology, colorectal cancer popular science articles, sharing of excellent papers and etc.

Fig.7：Screenshots of popular science articles and lectures

We also used other online promotions. On the Bilibili platform, team BIT and team YiYe-China conducted a live broadcast of colorectal cancer science promotion and synthetic biology promotion. The live broadcast introduced the clinical symptoms, hazards, mainstream of colorectal cancer, detection methods and more optimized detection methods conceived by the two teams respectively. This live broadcast has nearly 5,000 popularity points (approximately 500 people) watched this live broadcast. The main users of the Bilibili platform are young people aged 14-30. At the same time, the younger age and early onset of colorectal cancer are not well known to the public. Therefore, our live broadcast is aimed at the "target audience". Through this live broadcast, we can let them know more about colorectal cancer. So we can introduce our project to them and broaden the audience base of the product.
In this live broadcast, some researchers study CRC provided us with very valuable opinions during the live broadcast. His suggestions such as "the pros and cons of the current markers and the detection methods used" and "how to solve the problem of false positives" all make us think. Therefore, we also arranged special experiments to solve these problems in the follow-up project improvement. problem. At the same time, he also recommended that we increase the carrier experiment, and after in-depth communication with him, we will also take this as one of our future improvement directions.
MODULE 4
Community promotion
In order to increase the publicity of iGEM and our project, during the holidays we organized our team members to conduct community publicity activities in the communities where they live. They conducted iGEM and colorectal cancer research activities with relatives and friends, community residents, and community workers. Our community promotion covers all age groups. Our community propaganda has expanded the social influence of iGEM, which can help us let more people understand colorectal cancer, understand our project, and provide an audience basis for our project.

Fig.8：We introduce colorectal cancer to people of different ages

MODULE 5
Collaborations with other iGEMer
We have not only achieved external communication and publicity, but also talked with many teams in order to promote the development of our projects. This can help us learn from the experience of other teams and better carry out popular science activities.
With LZU-CHINA
2021.7.14
No. 5, South Street, Zhongguancun, Haidian District, Beijing
Our team members communicated with LZU-CHINA. The members of the two teams introduced and discussed the relevant content and technology of their respective teams, exchanged ideas with each other, discussed each other and made progress with each other.

Fig.9： Communication process

First two team leaders reported on the 2021 project. During the exchange, the LZU-CHINA asked us many constructive questions such as "miRNA is expressed at a high concentration in exosomes, how to extract exosomes? ", "Can miRNA be directly amplified as a sample" and etc. These questions have also led us to think about our incomplete considerations and provided a good idea for the improvement of our project. During the exchanges between the two teams, they exchanged experimental experience and experimental lessons, which helped us to improve the experimental plan in the future.
Team BIT and Team BIT-China
2021.7.18
No. 5, South Street, Zhongguancun, Haidian District, Beijing
We held an exchange meeting with the team BIT-China. At this exchange meeting, the members of the two teams reported on the progress of their completed projects and exchanged questions with each other. We have received many constructive suggestions during the exchange.

Fig.10: Communication process

Team BIT and YiYe-China
2021.7.19 and 2021.7.30
Online
We conducted two exchanges with the YiYe-China on the online Tencent meeting.
The first discussion forum was to exchange the projects of two teams. Both of our team’s projects were for early colorectal cancer screening. Through the exchanges, we complemented the methods of the two teams and exchanged the feasibility of the technology: how miRNA can make the CRISPR\Cas12 system recognize and work and etc. The cooperation and communication with YiYe-China allowed us to improve our understanding and design of the project and gave each other suggestions, which helped us to better complete the project.
At the same time, in response to the analysis of the questionnaire, we started the planning of the first online colorectal cancer science lecture. On the evening of July 30th, we launched an online colorectal cancer science lecture at Bilibili. This lecture was for the general public. The science popularization of colorectal cancer related knowledge let the public know more about colorectal cancer and helped us obtain suggestions for improvement of the project.
CCIC
2021.8.27-2021.8.29
Online
In the conference, each team carried out a comprehensive display of the project. The professional review teacher asked us questions and gave me suggestions on the project. Then they opened the exchange room for us to communicate with other teams.

Fig.11: Communication process

In the project, we asked questions about similar projects: Why did they choose the Crispr/Cas9 system and compared the difference with the Crispr/Cas12 system we chose. This helps us think about improving our projects and our popular science publicity.
In terms of HP and wiki, we consult with excellent teams for experience.

Fig.12: Communication process

When we listen to reports from other teams, we recorded their strengths to improve our learning. In this exchange, our team gained a lot. These experiences help us better carry out the follow-up popularization of science
MODULE 6
Meetup in Bluepha
2021.7.28
Communication in Bluepah
Bluepha is a synthetic biology high-tech enterprise founded by iGEMers. It has been committed to promoting and popularizing synthetic biology education and it is also a leader in the field of synthetic biology in China. Our team BIT went to the lab to visit and study and communicated with other four teams.

Fig.13：Meetup in Bluepha

Team BIT, team RDFZ, team GJU China and team NDNF-China all introduced their project and exchanged discussions with each other.

Fig.14：Report of four teams

In this exchange, the investors of the Bluepha gave guidance to our project and our members also put forward their ideas:
1. The selection of biomarkers must have the correct basis; How can miRNA joint inspection be tested simultaneously and separately? We need a clear method; Fig.15：Group photo
2. How to obtain relevant data of colorectal cancer patients?

Fig.15：Group photo

We discussed with them on the corresponding issues, which not only helped to improve our project, but also allowed us to modify our deficiencies in the preparation of science popularization. This help us can better carry out popular science publicity.
Summary
We are proud of making great progress in the field of science communication. We have created many online and offline synthetic biology activities for all kinds of people and let more people learn about colorectal cancer. Many people participate in these sub-projects. At the same time, we do not forget our own growth in activities and exchanges.
We are also discovering that we are not enough to provide better science knowledge in the course of exchanges and learning and science popularization.














Creat BY Beijing Institute of Technology

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