Team:TUDelft/Attributions
Attributions
During the development of AptaVita, each team member managed a specific task in line with a corresponding project module. We also received tremendous support from other parties, including supervisors, advisors, experts, and other relevant stakeholders. In addition to this, our sponsors gave us financial support, contributing to realizing our project. Here, we summarize what work has been done by which team member and thank others that have helped us out along the way.
Competition summary and team contributions
iGEM is offered as a course at our institution. As students, we apply to follow the iGEM course and hence join the competition. Two responsible instructors and several assistants guide the course. We started with the iGEM competition in mid-February 2021 and immediately dove into the brainstorming phase. This phase lasted to approximately the end of March 2021. From here on, we started to work in the laboratory and on the other relevant aspects of the project. By this time, we also assigned every team member a management position. The managers managed a specific sub-task of the project and those involved. An overview is shown in Tab. 1.
| Name | Role | Sub-Team |
|---|---|---|
| Pim van Beeck | Finance Manager | Dry Lab, Entrepreneurship, Hardware, Project Presentation Video, Sponsorship |
| Miriam Cammaert | Human Practices Manager | Education, Human Practices, Outreach, Project Presentation Video, Promo Video, Safety, Sponsorship, Wet Lab |
| Minke Gabriëls | Science & Safety Manager | Dry Lab, Human Practices, Project Presentation Video, Outreach, Safety, Wet Lab |
| Koen van Gent | Hardware Manager | Dry Lab, Hardware, Project Presentation Video |
| Riko Kuriki | Wiki Manager | Graphic Design, Human Practices, Project Presentation Video, Promo Video, Safety, Wet Lab |
| Milou van Nederveen | Outreach & Public Relations Manager (Part time) | Education, Outreach |
| Boyd Peters | Dry Lab Manager | Dry Lab, Education, Hardware, Project Presentation Video, Sponsorship |
| Federico Ramírez Gómez | Graphic Design Manager | Graphic Design, Human Practices, Outreach, Partnership, Project Presentation Video, Promo Video, Safety, Wet Lab |
| Laura Sierra Heras | Wet Lab Manager | Graphic Design, Human Practices, Project Presentation Video, Partnership, Safety, Wet Lab |
| Mathijs Verhoev | Team Leader | Dry Lab, Human Practices, Outreach, Partnership, Project Presentation Video, Promo Video, Safety, Sponsorship, Team Management |
| Loulotte Waling | Strategy Manager | Dry Lab, Entrepreneurship, Human Practices, Outreach, Partnership, Project Presentation Video, Sponsorship, Strategy |
External contributions
During our project, we received tremendous external support. In this section, we want to thank those that helped us realize the project that we envisioned.
We would like to thank:
General and project support
Principal Investigator
Dr. Christophe Danelon - Associate Professor at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
For advising us on all aspects of our project.
Instructors
Britte Bouchaut - PhD Candidate at Dept. of Biotechnology, Delft University of Technology, The Netherlands
Martin Holub - PhD Candidate at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
Ana Restrepo Sierra - PhD Candidate at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
Esengül Yildirim - Research Technician at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
For advising us on all aspects of our project.
Advisor
Ellen Winkler - Academic Counselor at Delft University of Technology, The Netherlands
For coaching us on team dynamics.
Others
Eline Doornenbal - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
and
Willem van Holthe - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
For in-depth sharing of their iGEM 2020 experiences with our team.
Charlotte Koster - PhD Candidate at Dept. of Biotechnology, Delft University of Technology, The Netherlands
For preparing our team for the iGEM competition and advising us on the trajectory of our project.
Matthew Turk - iGEM Ambassador to Europe, United Kingdom
and
Abigail Conner - iGEM Ambassador to Europe, United Kingdom
For their strategic support and guidance throughout our iGEM project.
Lab and office support
Dr. Daan Brinks - Assistant Professor at Dept. of Imaging Physics, Delft University of Technology, The Netherlands
and
Dr. Huma Safdar - Biolab Manager at Dept. of Imaging Physics, Delft University of Technology, The Netherlands
For giving us access to their lab space during the closure of our lab.
Esengül Yildirim - Research Technician at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
For the required laboratorium training and -support.
The Dept. of Bionanoscience at Delft University of Technology, The Netherlands
For providing us with an ML-1 laboratorium and office spaces.
The Dept. of Biotechnology at Delft University of Technology, The Netherlands
For providing us with office spaces.
Module specific support
Wet Lab support
Dr. Christophe Danelon - Associate Professor at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
For teaching us about cell free systems.
Dr. Anna Haagsma - Group Technician at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
For her advice on the sequencing strategy.
Javier Navarro - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
For his guidance to set up the urea-polyacrylamide gel protocols.
Sergio Tomás Martínez - PhD Candidate at Dept. of Biotechnology, Delft University of Technology, The Netherlands
For explaining the freeze-drier to us and letting us use it for the lyophilization experiments.
Ilja Westerlaken - Group Technician at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
For helping us buy reagents during the summer period.
Dry Lab support
Dr. Jan-Carel Diehl - Associate professor at Dept. of Sustainable Design Engineering, Delft University of Technology, The Netherlands
For providing valuable insight and feedback on the design of our dedicated hardware.
Rob Schrijen - Student MSc Integrated Product Design, Delft University of Technology, The Netherlands
For making a 3D printer available and helping us with the transition of STL files to Cura files.
Vera Smolders - Student MSc Integrated Product Design, Delft University of Technology, The Netherlands
For providing valuable input on the user-interface and user tests for the dedicated hardware.
Mojgan Talebi - Technician at Dept. of Chemical Engineering, Delft University of Technology, The Netherlands
For supervising us during the baking of the microfluidic paper.
Dimitri de Roos - Technician at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
For making adjustments to the hardware components post 3D printing.
Ramon van Valderen - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
For providing interesting perspectives and helpful tips on managing the dry lab.
OTRONIC Elektronica, Heemstede, The Netherlands: https://www.otronic.nl
For providing us with the necessary components of our dedicated hardware, free of charge.
Furthermore, we would like to thank Dieke Gabriëls, Stijn Heinen, Vincent Kruit, Tom de Laat, Héctor Maldonado, and Alexander Neutel for testing out our dedicated hardware and giving feedback on the user interface.
Human Practices support
Mujuni Achileo - Village Healthcare Worker in Uganda
For conducting the village healthcare survey in Uganda.
Dr. Lotte Asveld - Assistant Professor at Dept. of Biotechnology, Delft University of Technology, The Netherlands
For teaching us about Value-Sensitive Design, Safe-By-Design, and Responsible Innovation.
Celina van den Bank - Business Developer at the Koninklijk Instituut Van Ingenieurs, Den Haag, The Netherlands
For helping organize the philosophical discussion about synthetic biology with AptaVita as the case study.
Britte Bouchaut - PhD candidate at Dept. of Biotechnology, Delft University of Technology, The Netherlands
For being the chairwoman of our philosophical table.
Eline Doornenbal - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
and
Willem van Holthe - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
For advising us on our human practices work.
Dr. Ochora Moses - Medical Doctor at Mbarara Regional Referral Hospital, Mbarara, Uganda.
For helping us to get input from local village healthcare workers, providing us with local recipes, and general advice on our project from an Ugandan perspective.
Tosca Terra - Business Developer & Product and Services Manager at Healthy Entrepreneurs, Kampala, Uganda
For answering our questions about the healthy entrepreneurs and their inventory.
Special thanks to everyone who agreed to be interviewed by us:
Dr. Michel Bengtson (Leiden University Medical Center)
Dr. Mitasha Bharadwaj (Delft University of Technology)
Oliver Camp and Françoise Cattaneo (Global Alliance for Improved Nutrition)
Dr. Jan-Carel Diehl (Delft University of Technology)
Dr. Martin van Gijzen (Delft University of Technology)
Joyce Haddad (Flinders University)
Roel Kamerling (Global Initiative, Delft University of Technology)
Dr. Johnes Obungoloch (Mbarara University)
Dr. Moses Ochora (Mbarara Regional Referral Hospital)
Prof. dr. Ria Reis (Leiden University Medical Center)
Dr. Cécile van der Vlugt-Bergmans, Dr. Marja Agterberg, and Sam Krouwel (National Institute for Public Health and the Environment)
Read the full description of each interview here.
Safety support
David Calderón-Franco - PhD Candidate at Dept. of Biotechnology, Delft University of Technology, The Netherlands
For giving information and advice on doing experiments to test biocontamination of genetic material in the environment to analyze its safety.
Susanne Hage - Lab Coordinator at Dept. of Bionanoscience, Delft University of Technology, The Netherlands
For explaining the safety regulations and how to use labservant at Delft University of Technology, The Netherlands.
Dr. Cécile van der Vlugt - Senior risk assessor of GMOs, National Institute for Public Health and the Environment, Bilthoven, The Netherlands,
and
Dr. Marja Agterberg - Senior risk assessor of GMOs, National Institute for Public Health and the Environment, Bilthoven, The Netherlands,
and
Sam Krouwel - Policy and education advisor Safe-by-Design, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
For helping with- and giving feedback on the Safe-By-Design analysis of our project.
Sponsorship and Finance support
Loek Andriessen - Commissioner of External Affairs, S.V.N.B. Hooke, Delft University of Technology, The Netherlands
For providing us with an extensive acquisition training.
Shika Sebastian - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
For mentoring us on the financial aspects of our project.
Furthermore, we would like to thank the Frederick Gardner Cottrell Foundation for providing help during the obtention of the Impact Grant.
Partnership support
Luis Fernández-Pacios - Associate Professor at Madrid University of Technology, Spain
For helping us run the molecular dynamic simulations.
Javier Navarro - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
For advising us on how to run the electrophoresis mobility shift assays.
iGEM Vilnius-Lithuania - Vilnius University, Lithuania
For providing the aptamer sequences used in the electrophoretic shift assay experiments.
Collaboration support
Mai Bonomo - Team Captain at the TAU_Isreal iGEM team 2021, Tel Aviv, Israel
For setting up our workshop with the Agahozo-Shalom Youth Village (ASYV) and writing an ASYV guidebook for future iGEM teams.
iGEM Chung Cheng University 2021 team - National Chung Cheng University, Taiwan
For sharing their children’s book.
iGEM Groningen 2021 team - University of Groningen, The Netherlands
For sharing their comic book with us.
iGEM Ionis 2021 team - Sup’ Biotech School of Biotechnology Engineers, Paris, France
and
iGEM Northern BC 2021 team - University of Northern British Columbia, Prince George, Canada
For joining our vitamin collaboration meeting and helping out with the vitamin cookbook.
Colin Shae - Team member of the iGEM FSU 2021 team, Florida State University, The United States of America
For advising us on the Business Model Canvas.
Entrepreneurship support
Eugene Golov - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
For advising us on patenting of our project.
Blijke Kroezen - European Patent Attorney, V.O. Patents & Trademarks, Den Haag, The Netherlands
For advising us on patenting of our project.
Sylvia van Oorden - Project Manager, DA Cosmetics, Amersfoort, The Netherlands
For advising us on the pricing of products in developed countries.
Will Wright - Speaker 1 at the 2021 iGEM Summer Bootcamp, iGEM Foundation, Cambridge, The United States of America,
and
Ivan Rodriguez Jaubert - Speaker 2 at the 2021 iGEM Summer Bootcamp, iGEM Foundation, Cambridge, The United States of America,
and
Nikolas Keller - Speaker 3 at the 2021 iGEM Summer Bootcamp, iGEM Foundation, Cambridge, The United States of America
For overall guidance on how to tackle entrepreneurship.
Anita Ye - Senior Business Developer, SkylineDX, Rotterdam, The Netherlands
For providing feedback on our business model.
We would also like to thank the hosts of the 2021 iGEM Summer Bootcamp and breakout room guides for the overall organisation of the events.
Outreach and Education support
Daphne Klant - Worker at Jan Loris & Marie daycare, Delft, The Netherlands
For allowing us to set up a workshop at Jan Loris & Marie.
Tanja Klop - Coordinator Education at Science Center Delft, Delft University of Technology, The Netherlands
For helping us with learning how to set up a science workshop for children, and allowing us to present our project at the Science Days Delft.
Marit Lommelaars - Region Manager at Oud Geleerd Jong Gedaan, Amsterdam, The Netherlands
For helping to set up our lectures for elderly.
Dr. Ochora Moses - Medical Doctor at Mbarara Regional Referral Hospital, Mbarara, Uganda
For his help with the vitamin cookbook.
Dimmy van Ruiten - Wetenschapscommunicatie en Persvoorlichting at Delft University of Technology, The Netherlands
For providing media training and advising us on how to approach media platforms.
Dr. Sander Wildemans - Lecturer at Twente University, The Netherlands
For brainstorming with us about the educational module.
Graphic Design support
Jeroen Jacques - Student MSc Nanobiology, Delft University of Technology, The Netherlands
For co-realizing the live footage in our promotional video, and for the photography of our team members and group pictures.
QuickVision Creative - Delft, The Netherlands
For helping us with the animations of our project promotion video.
Enrique Zepeda Lopez - Freelancer, Mexico
For assessing and giving us his input in our logo animation on our wiki homepage.
For the use of the following visual elements: “Hands” icon by Tinashe Mugayi, “Chef hat” icon by Nawicon, “Government” icon by Wichai Wi, “Right” icon by Nikita Kozin, “Arrow” icon by Kiddo, “Survey” icon by popcornarts, “Scissors” icon by Kevin Sträter, “Trash can” icon by Gabriel Lemos Petry, “People” icon by Bonegolem, “Transport” icon by Mavadee, “Factory” icon by Jasmine Christine, “Chemistry” icon by ainul muttaqin, “City” icon by mohkamil, “Biology” icon by ibrandify, “Centrifruge” icon by Carl Holderness, “Blood lancet” by Muhamad Fuad Afandi, “Finger prick” icon by Peter van Driel, “Map Marker” icon by Mike Jewett, “Handshake” icon by Rudy Jaspers, “Magnifying glass” icon by Aneeque Ahmed, “Grass” icon by Hamish, “Rural” icon by Hamish,”Network” icon by fahmionline, “Target” icon by Hrbon, “Flag” icon by Nawicon, “Building” icon by Brand Mania, “Timer” icon by Graphik Designz and “City” icon by Gan Khoon Lay from The Noun Project (https://thenounproject.com).
Wiki support
Maartje Spaans - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
For providing us with advice on how to develop our wiki.
Team Management support
Nick Bowring - Student MSc Life Science & Technology, Delft University of Technology, The Netherlands
For advising us how to efficiently manage an iGEM team.