Team:Patras/Attributions
Attributions
We would also like to thank all the people who helped our team, iGEM Patras 2021, through any of its steps and actions anonymously!
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Team
Vasiliki Katsarou
Undergraduate student, Department of Pharmacy, University of Patras & one of the Team Leaders of the team.She organised and coordinated with the other team leaders all of the team’s work throughout the whole project. She was mainly occupied with the fundraising and she got in touch with the sponsors. Moreover, she contributed to the design of our wiki.
Maria Kousteliou
Undergraduate student, Department of Pharmacy, University of Patras & one of the Team Leaders of the team.She organised and coordinated with the other team leaders all of the team’s work throughout the whole project. She was the head of our Public Relations team, she contributed to the design of our Human Practices' strategy while she was responsible for the Integrated Human Practice.
Dimitrios Spanos
Undergraduate student, Department of Pharmacy, University of Patras & one of the Team Leaders of the team.He organised and coordinated with the other team leaders all of the team’s work throughout the whole project. He had the general supervision of the project's development process, the finance activities, the Human Practices' development, and the Wet Lab's experiments.
Georgios Varitis
Pharmacist BSc, Department of Pharmacy, University of Patras & one of the Team Leaders of the team.He organized and coordinated with the other team leaders all of the team's work throughout the whole project. So, he mainly supervised the development of our project.
Evanthia Iliopoulou
Pharmacist, MSc Student at Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, University of Patras & one of Wet Lab Researchers of the team.She took part in the project development process and performed all the experiments, such as parts design, site-directed mutagenesis procedures in eukaryotic cells and immunoblotting.
Georgios Psarias
Undergraduate student, Department of Pharmacy, University of Patras & one of Wet Lab Researchers & Graphic Designer of the team.He took part in the project development process and performed all the experiments, such as parts design, site-directed mutagenesis procedures in eukaryotic cells and immunoblotting. He also designed the graphics needed to promote our team and explain our scientific actions to the public.
Georgios Bampounis
Undergraduate student, Department of Chemical Engineering, University of Patras.He took part in some experiments regarding the site-directed mutagenesis procedures in eukaryotic cells.
Alexandra Kyriakopoulou
Pharmacist BSc, Department of Pharmacy, University of Patras & one of Dry Lab Researchers and member of Public Relations.She helped with the literature review and she used molecular simulation methods like docking in order to find the interaction between the rarely mutated enzymes CYP2D6 and CYP2C19 and the chemical compound mephenytoin and clopidogrel respectively. Moreover, she was a member of the Public Relations team and she engaged with Science Communication.
Konstantinos Laimos Geranios
Pharmacist, MSc student at Laboratory of Medicinal Chemistry, Department of Pharmacy, University of Patras & one of our Dry Lab team members.He helped with the literature review and he used molecular simulation methods like docking in order to find the interaction between the rarely mutated enzymes CYP2D6 and CYP2C19 and the chemical compound mephenytoin and clopidogrel respectively.
Georgios Andronikidis
Computer Engineer, Department of Computer Science, University of Thessaly & one of our Dry Lab team members.He is our Wiki creator and he assisted in Science Communication.
Ariadne Damanaki
Undergraduate student, Department of Pharmacy, University of Patras & one of our Human Practices team members and Social Media team.She was in our Public Relations team, responsible for our social media context and the Integrated Human Practice.
Konstantinos Fragkakis
Undergraduate student, Department of Economics, Open University of Cyprus & a member in the Fundraising and Public Relations team.He contacted different companies and sponsors, he did research about the cost effectiveness for our project and he was responsible for making the podcasts.
Lefteris Bochalis
Undergraduate student, Department of Pharmacy, University of Patras & a member in the Fundraising and Public Relations team.He got in touch with different companies and sponsors. Moreover, he was responsible for the partnership of our team with team Thessaloniki.
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Advisors
Stavroula Stasinou
Graphic & Web Designer, Computer Technology Institute and Press "Diophantus", Specialised in Creative Direction and branding.She helped us design all the graphics needed to promote our team and explained our scientific actions to the public.
Ioannis Daramouskas
Diploma Computer Engineer and Informatics, PhD candidate at Applied Mechanics & Vibrations Laboratory, Department of Mechanical Engineering & Aeronautics, University of Patras and Software Engineer, Computer Technology Institute and Press "Diophantus".He helped us to create our Wiki.
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Instructors
Stavroula Siamoglou
Pharmacist MSc, Lab manager & PhD candidate at Pharmacogenomics and Individualized Therapy, Department of Pharmacy, University of Patras.She guided us on our first steps in our literature review and information about our team's scientific field, pharmacogenomics. She also took part in science communication.
Maria Koromina
Post-doctoral Researcher in Bioinformatics and Statistical Genetics in the Laboratory of Pharmacogenomics and Individualised Therapy, School of Pharmacy, University of Patras.She was responsible for the Bioinformatic aspect of our project and trained us on the basics of NGS analysis. She took part in the project development process, and she provided guidance through our first steps.
Diana-Hortensia Portan
Researcher, CCAMF-UMFST, Tg. Mures, Romania , Academic Fellow, Mech. Eng. & Aeronautics Department, University of Patras, Greece.She took part in the project development process and trained us on fundamental techniques and protocols in cell cultures.
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Supervisors
Georgios P. Patrinos
Professor of Pharmacogenomics and Pharmaceutical Biotechnology, Director of Pharmacogenomics and Individualized Therapy, Laboratory, Department of Pharmacy, University of Patras & Primary Principal Investigator of our team.He allowed us to use the Laboratory of Pharmacogenomics & Individualized Medicine in order to perform our experiments. He also provided scientific assistance and mentored us throughout the development of our project.
Vasilis Kostopoulos
Professor, Director of Applied Mechanics & Vibrations Laboratory, Department of Mechanical Engineering & Aeronautics, University of Patras & Secondary Principal Investigator of our team.He allowed us to use his laboratory in order to perform our experiments.
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Project Support & Advice
Jessica Martyn
iGEM Mentor, Post-Doc in Biology of Intracellular Bacteria at Institut Pasteur.She mentored through the whole project, especially in the wet lab and we discussed our Human Practices and science communication events. Moreover, she helped us with the partnership.
Ioannis Vizirianakis
Assistant Professor of Molecular Pharmacology and Pharmacogenomics, Department of Pharmaceutical Sciences, AUTH.He proposed the way to include measurements upon the quantity of the enzymes (CYP2D6 and CYP2C19) produced after the site-directed mutagenesis on them.
Masahiro Hiratsuka
Ph.D. Associate Professor, Laboratory of Pharmacotherapy of Life-Style Related Diseases Graduate School of Pharmaceutical Sciences, Tohoku University, JapanThe Western blotting and the measurements of metabolites on UPLC and LC/MS-MS, for determing the enzymes' activity were conducted on their Laboratory and the results provided to us.
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Participation Support
Ioannis Iliopoulos
Pro Photo-Video Grapher & Youtuber & FreelancerHe videotaped and edited our team's Team Presentation Video.
Stavros Papastavrou
Video Editor and Motion Graphics expertHe edited our promotional video.
Sotirios Nikolaropoulos
Professor & Director of the Laboratory of Medicinal Chemistry, Department of Pharmacy, University of Patras & President of the Department of PharmacyHe gave us his permission as the President of the Department of Pharmacy to film spaces of its building and laboratories.
Copy Corner
Printing shop which printed our cards for our board games and our comics.
Moreas
Printing shop which created our print-on T-shirts.
Jamba Copy
They created our team’s banner and stickers.
Moreover,we would like to thank the following sites that support us through a publication about our team.
PharmaManage
ONMED
Healthmag
f.kosmos
DailyPharmaNews
Clinical Pharmacist
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Human Practices
Georgios P. Patrinos
Professor of Pharmacogenomics and Pharmaceutical Biotechnology, Director of Pharmacogenomics & Personalized Medicine Laboratory, Department of Pharmacy, University of PatrasHe advised us about Pharmacogenomics and what obstacles must be overcome to achieve the ideal personalized treatment.
Sotiria Boukouvala
Associate Professor in Molecular Genetics, Director, Laboratory of Pharmacogenomics-Toxicogenomics, Democritus University of Thrace, Department of Molecular Biology and GeneticsShe emphasized two essential liver enzymes, CYP2D6 and CYP2C19, as they play a significant role in the metabolism of many prescribed drugs, and she suggested we search in databases, such as Pharm Var, Pharmacogenomics knowledge base, Pharmacogenomics biomarkers in order to find exactly what we need to start our laboratory procedures.
Daniel J. Mueller
Professor, Head, Pharmacogenetics Research Clinic & Staff Psychiatrist, Mood and Anxiety ServicesHe verified that even though many patients undergo pharmacogenomic testing and he suggested we work with psychiatric drugs, such as antidepressants and antipsychotics, which CYP2D6 metabolizes.
Sotiris Patsilinakos
Medical Director of the Cardiological Department of Konstantopoulio General Hospital of Nea Ionia, Athens, Greece.He confirmed the importance of the CYP2D6 and CYP2C19 enzymes and suggested we do some research upon clopidogrel, an antiplatelet agent.
Konstantinos Nikitidis
General Practitioner - Expert in Personalised Medicine through Pharmacogenetics.He made it clear that a test that gives results more quickly and is more affordable would be much more helpful. He also listed several drugs that he thinks we should take under consideration, such as clopidogrel and opioid analgesics.
Diamantis Klimentidis
Clinical Pharmacist, Msc at Clinical Pharmacy, MSc at Management of Aging and Chronic Diseases.He highlighted the importance of convincing doctors about the value of pharmacogenomic testing and suggested we present our project in clinics and doctors. He made us aware of the Laboratory of the Research of Medical Law and Bioethics in A.U.Th School of Law.
Argyris Symeonidis
Vice President at Gaucher Disease Task Force of the European Hematology Association (EHA)He reassured us about the importance of making Pharmacogenomics more known and explained why it is not widely applied.
Paraskevi Panagopoulou
Psychiatrist, psychotherapist at Social Security Institution IKAShe agreed that Pharmacogenomics would be a valuable tool in psychiatry because there are difficult disorders without an excellent existing treatment.
Argiro Sgourou
Assistant Professor, School of Science and Technology (SST), Hellenic Open University (HOU)She was very helpful by providing us the necessary knowledge concerning the functional annotation of cells and she urged us to use site-directed mutagenesis in eukaryotic cells.
Maria Koromina
Post-doctoral Researcher in Bioinformatics and Statistical Genetics in the Laboratory of Pharmacogenomics and Individualised Therapy, School of Pharmacy, University of PatrasWe discussed how we could certify a novel variant and whether it would be useful to include rare variants in our panel. She also made a comparison between NGS and the Sanger method.
Dionisis Panagiotis Kintos
PhD Candidate in the Laboratory of Medicinal Chemistry, Department of Pharmacy, University of PatrasHe highlighted the importance of determining the stability of the variant proteins using denaturation experiments at higher temperatures and to determine structure-function relationships.
Sotirios Nikolaropoulos
Professor & Director of the Laboratory of Medicinal Chemistry, Department of Pharmacy, University of Patras & President of the Department of PharmacyHe helped to understand how we can implement 3 Dimensional Structural Modelling in Pharmacogenomics.
Christina Mitropoulou
Managing Director and Senior Health Economist, The Golden Helix FoundationShe analyzed the potential economic problems and the economic policy to be followed.
Athina Eleftheraki
Msc in Toxicology at Karolinska Institutet and iGEM Stockholm 2019 team LeaderShe gave us a lot of information about iGEM competition and advised us in order to succeed, she suggested that the Docking procedure was ideal for modeling our project.
Georgia Papanikolaou
PhD Candidate at the Department of Molecular Biology and Genetics, Democritus University of ThraceShe compared all the existing NGS devices and we also discussed together how important Pharmacogenomics is in clinical practice and how important it is to do research in it and find more and more variants and their consequences.
Anastasios Galanis
Scientist in Oxford Nanopore Technologies, Academia and Research Steering Group Member at After iGEMHe recommended to use Oxford Nanopore MinION.
Research Labs of Faculty of Law (Aristotle University of Thessaloniki)
They informed us about the legal and ethical issues that can arise from a project like ours and how we can prevent them.
GENEKOR
A Molecular Biology Laboratory, focused in Oncology, Cardiology, Neurology and Pharmacogenetics.They gave us important information about the possible future steps for promoting our project, its advantages and how to convince its potential users to get advance of it.
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Governmental Organizations
Virginia Safra
Department of Medical Devices, National Organization for Medicines (ΕΟΦ)She informed us about the process a diagnostic tool needs to be approved and how we could make it suitable for approval by the National Organization for Medicines.
Iordanis Gravanis
MD PhD Head of Office Scientific Advice Scientific Evidence Generation Department European Medicines Agency (EMA)He highlighted that any innovative technology related to drug development is positively examined to get approval.
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Education & Public Engagement & Inclusion
National Federation for the Blind of Greece
They translated our comic into the Braille system.
Peripheral Association for the Blind of Western Greece
They assisted in handing out our comics translated in Braille to the Blind and Visually Impaired Community
Ioannis Sfaelos
Director of the UoP’s Experimental High SchoolHe gave us the opportunity to present our project and team to the pupils of the Experimental high school.
Natassa Gogou
Undergraduate student, Department of Political Engineer, University of Patras & Producer at Up FM RadioShe gave us the opportunity through her broadcast to share our project with her audience.
George Stathis
Expert of BSL in HandsUp AgencyHe translated our promotional video to BSL.
Georgia Paraskevopoulou
Professional educator and actressShe helped us create our comic.
Roza Pavlidou
Primary school - kindergarten teacherShe helped us to create our comic.
Superiors of ΚΕΔΕΑ Thessaloniki
They granted us access so we could host the seminar “It’s all about iGEM: A SynBio Day” in Thessaloniki
We would like to thank the following associations that gave us the opportunity to present our project at their conferences.
Experimental High School of University of Patras
Experimental School of University of Macedonia
Tutorial school for secondary education “Κytaro”
Helmsic
ESFIE
Athens Science Festival
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Acknowledgments
Leandros Tsiotos
iGEM Ambassador for Europe (EU)He helped us by guiding us many times as far as the competition requirements are concerned. He was also a guest in one of our podcasts episodes.
Dimitris Michailidis
iGEM Judging Committee Member and Veteran Judge Award winner at iGEM 2020 CompetitionHe gave us advice as far as an iGEM Judge experience is concerned in the "Mare nostrum iGEM Meetup", organized by our team, and in one of our podcasts episodes.
Carolina Elizondo
Global coordinator of iGEM AmbassadorsShe made a speech upon her iGEM experience in our “Mare nostrum iGEM Meet-Up”.
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Sponsors
Financial Support
GENEKOR M.S.A
Pfizer
Special Account of Funds and Research of the University of Patras (ΕΛΚΕ)
Material Sponsors
IDT Technologies
New England Βiolabs
Monday