Phase I
Astrobio 2020 and Astroyeast 2021 are a two-year iGEM project. In year 1, we built Astrobio, an R&D platform to facilitate experimental research and biomanufacturing applications in space. We used AstroBio to compare microgravity-induced gene expression changes in yeast across different studies and to isolate gene promoter candidates that are specifically altered by microgravity.
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Phase II
This year, we are using the selected gene promoters to construct a microgravity-induced stress reporter using Green Fluorescent Protein. We will then perform adaptive lab evolution (ALE) mutagenesis to further increase diversity in our reporter strain populations...
