Difference between revisions of "Team:Shanghai Metropolis"
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<!--内容--> | <!--内容--> | ||
<div class="content"> | <div class="content"> | ||
| + | <!--ABSTRACT--> | ||
<section class="abstract article"> | <section class="abstract article"> | ||
<h1 class="title">ABSTRACT</h1> | <h1 class="title">ABSTRACT</h1> | ||
| − | <h2 class="title big blue"> | + | <h2 class="title big blue" style="margin: 40px 0 34px 0"> |
Hand, Foot, and Mouth Disease | Hand, Foot, and Mouth Disease | ||
</h2> | </h2> | ||
<div class="bottom"> | <div class="bottom"> | ||
| − | <p>Hand-foot-and-mouth disease (HFMD) is a contagious viral infection, mostly occurring in children | + | <p>Hand-foot-and-mouth disease (HFMD) is a contagious viral infection, mostly occurring in children under |
| − | + | the age of five. The condition is caused by a series of enteroviruses, including EV71, and VP1 is one of | |
| − | the age of five. The condition is caused by a series of enteroviruses, including EV71, and VP1 is | + | |
| − | + | ||
its pathogenic subunits. Since many of the infected children may be afraid of traditional | its pathogenic subunits. Since many of the infected children may be afraid of traditional | ||
| − | injection-based vaccines, we are trying to develop an EV71 oral vaccine that will gain higher | + | injection-based vaccines, we are trying to develop an EV71 oral vaccine that will gain higher compliance |
| − | + | among infant patients. Using E. coli and L. casei as the expressive system, we express the plasmids we | |
| − | among infant patients. Using E. coli and L. casei as the expressive system, we express the plasmids | + | |
| − | + | ||
constructed, pGEX-6P-1-VP1 and pGEX-6P-1-VP1-LTB. We hope that our project will shed light on the | constructed, pGEX-6P-1-VP1 and pGEX-6P-1-VP1-LTB. We hope that our project will shed light on the | ||
| − | possibility and practicability of the EV71 subunit oral vaccine and pave the way for a much safer, | + | possibility and practicability of the EV71 subunit oral vaccine and pave the way for a much safer, more |
| − | + | ||
convenient, and efficient oral vaccine for children to defend against HFMD.</p> | convenient, and efficient oral vaccine for children to defend against HFMD.</p> | ||
| − | <img src=" | + | <img src="T--Shanghai_Metropolis--img_index_1.png" alt=""> |
</div> | </div> | ||
</section> | </section> | ||
| + | <!--PROMOTIONAL VIDEO--> | ||
<section class="promotional article"> | <section class="promotional article"> | ||
<h1 class="title">PROMOTIONAL VIDEO</h1> | <h1 class="title">PROMOTIONAL VIDEO</h1> | ||
Revision as of 07:04, 9 September 2021
ABSTRACT
Hand, Foot, and Mouth Disease
Hand-foot-and-mouth disease (HFMD) is a contagious viral infection, mostly occurring in children under the age of five. The condition is caused by a series of enteroviruses, including EV71, and VP1 is one of its pathogenic subunits. Since many of the infected children may be afraid of traditional injection-based vaccines, we are trying to develop an EV71 oral vaccine that will gain higher compliance among infant patients. Using E. coli and L. casei as the expressive system, we express the plasmids we constructed, pGEX-6P-1-VP1 and pGEX-6P-1-VP1-LTB. We hope that our project will shed light on the possibility and practicability of the EV71 subunit oral vaccine and pave the way for a much safer, more convenient, and efficient oral vaccine for children to defend against HFMD.
