Team:CKWA-China/Description

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Inspiration

1. A major problem in cancer.

Recurrence of cancer after treatment is a major problem facing humans today, and cancer recurrence is a great threat for cancer patients. Among them, overexpression of c-myc protein is closely related to this process, and patients with overactivation of c-myc gene in cancer cells tend to have poor prognosis.

1.1 What are myc genes?

myc genes have been shown to be a class of regulatory genes that are transcription factors that can encode myc-like proteins to become transcription factors transcription factors. they are essential for cell growth, metabolism and tissue development.

1.2 Impact of myc in cancer

They are essential for cell growth, metabolism and tissue development. Also, MYC is an important group of oncogenes. c-MYC is aberrantly expressed in about 30-50% of human malignancies and plays an extremely important role in affecting cell growth, proliferation, differentiation, apoptosis, as well as cell metabolism and malignant transformation. aberrantly high expression of c-MYC is associated with poor prognosis in many human cancers. Translated with www.DeepL.com/Translator (free version)

1.3 C-myc genes

The Myc family consists of three related human genes: - c-myc (MYC), the first gene to be discovered in this family - l-myc (MYCL) - n-myc (MYCN)

We then recognized an absence in both detection and treatment of Soft Rot Disease. Therefore, we understood the importance of a bio-control solution that is not only effective but also environmentally-friendly. Based on knowledge of the field of synthetic biology, we started to come up with different approaches to soft rot detection and treatment.

Interview（Potato Center Asia-Pacific Headquarter）

We met with senior staffs of the potato center Asia-Pacific Headquarter to learn about the current detection and treatments of potato diseases. We then visited their workplace, which accounted for a large proportion of the current potato-agricultural development. We presented our initial concept to the experts (including the chairman of the potato center, Mr. Lu) and audited a group meeting on agricultural pharmacology. Through the discussions with them, we became more aware of the consequences of Soft Rot disease and the importance of creating an effective bio-control solution.