Difference between revisions of "Team:CKWA-China/Human Practices"

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                <h1>Aside</h1>
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                    <li><a href="https://2021.igem.org/Team:CKWA-China">Home</a></li>
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                    <li>Aside</li>
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                            <h2 class="point" id="point-1">Inspiration</h2>
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<h3 class="point" id="point-2">1. A major problem in cancer.</h3>
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                            <p>
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Recurrence of cancer after treatment is a major problem facing humans today, and cancer recurrence is a great threat for cancer patients. Among them, overexpression of c-myc protein is closely related to this process, and patients with overactivation of c-myc gene in cancer cells tend to have poor prognosis.</p>
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<h3 class="point" id="point-2">1.1 What are myc genes?</h3>
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                            <p>
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myc genes have been shown to be a class of regulatory genes that are transcription factors that can encode myc-like proteins to become transcription factors transcription factors. they are essential for cell growth, metabolism and tissue development.</p>
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<h3 class="point" id="point-2">1.2 Impact of myc in cancer</h3>
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<p>
  
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They are essential for cell growth, metabolism and tissue development. Also, MYC is an important group of oncogenes. c-MYC is aberrantly expressed in about 30-50% of human malignancies and plays an extremely important role in affecting cell growth, proliferation, differentiation, apoptosis, as well as cell metabolism and malignant transformation. aberrantly high expression of c-MYC is associated with poor prognosis in many human cancers.
  
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Translated with www.DeepL.com/Translator (free version)
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<h3 class="point" id="point-2">1.3 C-myc genes</h3>
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<h1>Human Practices</h1>
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The Myc family consists of three related human genes:
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<p>
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- c-myc (MYC), the first gene to be discovered in this family
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At iGEM we believe societal considerations should be upfront and integrated throughout the design and execution of synthetic biology projects. “Human Practices” refers to iGEM teams’ efforts to actively consider how the world affects their work and their work affects the world. Through your Human Practices activities, your team should demonstrate how you have thought carefully and creatively about whether your project is responsible and good for the world. We invite you to explore issues relating (but not limited) to the ethics, safety, security, and sustainability of your project, and to show how this exploration feeds back into your project purpose, design, and execution.
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- l-myc (MYCL)
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- n-myc (MYCN)
 
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                                        <p>We then recognized an absence in both detection and treatment of Soft Rot Disease. Therefore, we understood the importance of a bio-control solution that is not only effective but also environmentally-friendly. Based on knowledge of the field of synthetic biology, we started to come up with different approaches to soft rot detection and treatment.</p>
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<p>Please note you can compete for the Silver Medal criterion #3, Gold Medal criterion #1 and the Best Integrated Human Practices prize with this page. </p>
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                                        <div class="image"><a href="./images/image-2.jpg" class="lightbox-image"><img src="https://static.igem.org/mediawiki/2020/c/cb/T--iBowu-China--keystone1.png" alt=""></a>
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<p>For more information, please see the <a href="https://2021.igem.org/Human_Practices">Human Practices Hub</a>.</p>
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<p>On this page, your team should document all of your Human Practices work and activities. You should write about the Human Practices topics you considered in your project, document any activities you conducted to explore these topics (such as engaging with experts and stakeholders), describe why you took a particular approach (including referencing any work you built upon), and explain if and how you integrated takeaways from your Human Practices work back into your project purpose, design and/or execution. </p>
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                            <h3 class="point" id="point-2">Interview（Potato Center Asia-Pacific Headquarter）</h3>
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                            <p>We met with senior staffs of the potato center Asia-Pacific Headquarter to learn about the current detection and treatments of potato diseases. We then visited their workplace, which accounted for a large proportion of the current potato-agricultural development. We presented our initial concept to the experts (including the chairman of the potato center, Mr. Lu) and audited a group meeting on agricultural pharmacology. Through the discussions with them, we became more aware of the consequences of Soft Rot disease and the importance of creating an effective bio-control solution.</p>
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                            <h3 class="point" id="point-3">Experts</h3>
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                            <p>Our team had the pleasure of meeting with Dr. Flemming Bensenbacher on 5th July 2019. Dr. Bensenbacer is an academician of the Royal Danish academy of Sciences and President of Carlsberg Foundation. He shared his journey in scientific research with us and the problems he encountered and tackled. We presented our project to him and hosted an interview with questions relating to the application of synthetic biology. This opportunity was crucial to us as we gained from it a valuable depth of knowledge in the potential future pathways of our product development.</p>
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                            <p>
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                                <video style="width: 100%;" src="video/mda-kc21c5bv2fig3ieu.mp4" controls="“ture”"></video>
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                                                <p>I could write some video notes here, a little bit more introduction.
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<h3>Silver Medal Criterion #3</h3>
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<p>Explain how you have determined your work is responsible and good for the world.</p>
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                                                <p>I could write some video notes here, a little bit more introduction.
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                                                </p>
  
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<h3>Gold Medal Criterion #1</h3>
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<p>Demonstrate how your team responded to your human practices reflections, research, and/or engagement. You should show how your activities impacted your project purpose, design and/or execution.
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<p>Please see the <a href="https://2021.igem.org/Judging/Medals">2021 Medals Page</a> for more information. </p>
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                                                <p>I could write some video notes here, a little bit more introduction.
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<h3>Best Integrated Human Practices Special Prize</h3>
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                                    <a href="#point-1">Literature Review</a>
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<p>To compete for the <a href="https://2021.igem.org/Judging/Awards">Best Integrated Human Practices prize</a>, please describe your work on this page  and also fill out the description on the <a href="https://2021.igem.org/Judging/Judging_Form">judging form</a>. </p>
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                                      <li><a href="">Literature Review</a></li>
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<p>How does your project affect society and how does society influence the direction of your project? How might ethical considerations and stakeholder input guide your project purpose and design and the experiments you conduct in the lab? How does this feedback enter into the process of your work all through the iGEM competition? Document a thoughtful and creative approach to exploring these questions and how your project evolved in the process to compete for this award!</p>
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                                      <li><a href="">Literature Review</a></li>
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                                      <li><a href="">Literature Review</a></li>
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                                      <li><a href="">Literature Review</a></li>
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                                  <a href="#point-2">Interview</a>
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                                      <li><a href="">Interview</a></li>
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<h3>Inspiration</h3>
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                                      <li><a href="">Interview</a></li>
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<p>You can look at what other teams did to get some inspiration! <br />
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                                      <li><a href="">Interview</a></li>
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Here are a few examples:</p>
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<ul>
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<li><a href="https://2019.igem.org/Team:Thessaly/Human_Practices">2019 Thessaly</a></li>
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                                <li><a href="#point-3">Experts</a></li>
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<li><a href="https://2019.igem.org/Team:Linkoping_Sweden/Human_Practices">2019 Linkoping Sweden</a></li>
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<li><a href="https://2019.igem.org/Team:FDR-HB_Peru/Human_Practices">2019 FDR HB Peru</a></li>
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<li><a href="https://2020.igem.org/Team:William_and_Mary/Human_Practices">2020 William and Mary</a></li>
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<li><a href="https://2020.igem.org/Team:Rochester/Human_Practices">2020 Rochester</a></li>
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            </div>
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<li><a href="https://2020.igem.org/Team:Leiden/Human_Practices">2020 Leiden</a></li>
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        </div>
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<li><a href="https://2020.igem.org/Team:Baltimore_BioCrew/Human_Practices">2020 Baltimore BioCrew</a></li>
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Revision as of 01:28, 9 October 2021

Aside

Inspiration

1. A major problem in cancer.

Recurrence of cancer after treatment is a major problem facing humans today, and cancer recurrence is a great threat for cancer patients. Among them, overexpression of c-myc protein is closely related to this process, and patients with overactivation of c-myc gene in cancer cells tend to have poor prognosis.

1.1 What are myc genes?

myc genes have been shown to be a class of regulatory genes that are transcription factors that can encode myc-like proteins to become transcription factors transcription factors. they are essential for cell growth, metabolism and tissue development.

1.2 Impact of myc in cancer

They are essential for cell growth, metabolism and tissue development. Also, MYC is an important group of oncogenes. c-MYC is aberrantly expressed in about 30-50% of human malignancies and plays an extremely important role in affecting cell growth, proliferation, differentiation, apoptosis, as well as cell metabolism and malignant transformation. aberrantly high expression of c-MYC is associated with poor prognosis in many human cancers. Translated with www.DeepL.com/Translator (free version)

1.3 C-myc genes

The Myc family consists of three related human genes: - c-myc (MYC), the first gene to be discovered in this family - l-myc (MYCL) - n-myc (MYCN)

We then recognized an absence in both detection and treatment of Soft Rot Disease. Therefore, we understood the importance of a bio-control solution that is not only effective but also environmentally-friendly. Based on knowledge of the field of synthetic biology, we started to come up with different approaches to soft rot detection and treatment.

Interview（Potato Center Asia-Pacific Headquarter）

We met with senior staffs of the potato center Asia-Pacific Headquarter to learn about the current detection and treatments of potato diseases. We then visited their workplace, which accounted for a large proportion of the current potato-agricultural development. We presented our initial concept to the experts (including the chairman of the potato center, Mr. Lu) and audited a group meeting on agricultural pharmacology. Through the discussions with them, we became more aware of the consequences of Soft Rot disease and the importance of creating an effective bio-control solution.

Experts

Our team had the pleasure of meeting with Dr. Flemming Bensenbacher on 5th July 2019. Dr. Bensenbacer is an academician of the Royal Danish academy of Sciences and President of Carlsberg Foundation. He shared his journey in scientific research with us and the problems he encountered and tackled. We presented our project to him and hosted an interview with questions relating to the application of synthetic biology. This opportunity was crucial to us as we gained from it a valuable depth of knowledge in the potential future pathways of our product development.

I could write some video notes here, a little bit more introduction.

I could write some video notes here, a little bit more introduction.

I could write some video notes here, a little bit more introduction.