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{{IGEM_TopBar}} | {{IGEM_TopBar}} | ||
− | {{CKWA-China}} | + | {{CKWA-China/header}} |
<html> | <html> | ||
+ | <!--Main Slider--> | ||
+ | <section class="main-slider"> | ||
+ | <div class="rev_slider_wrapper fullwidthbanner-container" id="rev_slider_one_wrapper" data-source="gallery"> | ||
+ | <div class="rev_slider fullwidthabanner" id="rev_slider_one" data-version="5.4.1"> | ||
+ | <ul> | ||
+ | <!-- Slide 1 --> | ||
+ | <li data-description="Slide Description" data-easein="default" data-easeout="default" | ||
+ | data-fsmasterspeed="1500" data-fsslotamount="7" data-fstransition="fade" | ||
+ | data-hideafterloop="0" data-hideslideonmobile="off" data-index="rs-1681" | ||
+ | data-masterspeed="default" data-param1="" data-param10="" data-param2="" data-param3="" | ||
+ | data-param4="" data-param5="" data-param6="" data-param7="" data-param8="" data-param9="" | ||
+ | data-rotate="0" data-saveperformance="off" data-slotamount="default" | ||
+ | data-thumb="https://static.igem.org/mediawiki/2021/c/c1/T--CKWA-China--slide3.jpg" data-title="Slide Title" | ||
+ | data-transition="parallaxvertical"> | ||
+ | <img alt="" class="rev-slidebg" data-bgfit="cover" data-bgparallax="10" | ||
+ | data-bgposition="center center" data-bgrepeat="no-repeat" data-no-retina="" | ||
+ | src="https://static.igem.org/mediawiki/2021/c/c1/T--CKWA-China--slide1.jpg"> | ||
− | <div class=" | + | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" |
− | < | + | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" |
− | + | data-type="text" data-height="none" data-width="['700','700','700','700']" | |
+ | data-whitespace="normal" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['-150','-150','-120','-120']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <h4>We Proudly Service</h4> | ||
+ | </div> | ||
− | < | + | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" |
+ | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | ||
+ | data-type="text" data-height="none" data-width="['1000','700','700','700']" | ||
+ | data-whitespace="normal" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['-60','-60','-60','-60']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <h2>These Metro Markets</h2> | ||
+ | </div> | ||
− | </div> | + | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" |
+ | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | ||
+ | data-type="text" data-height="none" data-whitespace="normal" | ||
+ | data-width="['700','700','550','550']" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['30','40','0','30']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[-100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <div class="text">Flooring is a family-owned and operated business. we have been | ||
+ | installing floorssince 1992 and have installed flooring and Tilling</div> | ||
+ | </div> | ||
+ | </li> | ||
+ | <!-- Slide 2 --> | ||
+ | <li data-description="Slide Description" data-easein="default" data-easeout="default" | ||
+ | data-fsmasterspeed="1500" data-fsslotamount="7" data-fstransition="fade" | ||
+ | data-hideafterloop="0" data-hideslideonmobile="off" data-index="rs-1682" | ||
+ | data-masterspeed="default" data-param1="" data-param10="" data-param2="" data-param3="" | ||
+ | data-param4="" data-param5="" data-param6="" data-param7="" data-param8="" data-param9="" | ||
+ | data-rotate="0" data-saveperformance="off" data-slotamount="default" | ||
+ | data-thumb="https://static.igem.org/mediawiki/2021/c/c1/T--CKWA-China--slide1.jpg" data-title="Slide Title" | ||
+ | data-transition="parallaxvertical"> | ||
− | < | + | <img alt="" class="rev-slidebg" data-bgfit="cover" data-bgparallax="10" |
+ | data-bgposition="center center" data-bgrepeat="no-repeat" data-no-retina="" | ||
+ | src="https://static.igem.org/mediawiki/2021/c/c1/T--CKWA-China--slide2.jpg"> | ||
− | < | + | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" |
− | + | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | |
− | + | data-type="text" data-height="none" data-width="['700','700','700','700']" | |
− | + | data-whitespace="normal" data-hoffset="['15','15','15','15']" | |
− | + | data-voffset="['-150','-150','-120','-120']" data-x="['left','left','left','left']" | |
− | + | data-y="['middle','middle','middle','middle']" | |
− | + | data-frames='[{"from":"y:[100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | |
− | </div> | + | <h4>We Proudly Service</h4> |
+ | </div> | ||
+ | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" | ||
+ | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | ||
+ | data-type="text" data-height="none" data-width="['1000','700','700','700']" | ||
+ | data-whitespace="normal" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['-60','-60','-60','-60']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <h2>These Metro Markets</h2> | ||
+ | </div> | ||
− | <div class=" | + | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" |
− | <div class=" | + | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" |
− | <div | + | data-type="text" data-height="none" data-whitespace="normal" |
+ | data-width="['700','700','550','550']" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['30','40','0','30']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[-100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <div class="text">Flooring is a family-owned and operated business. we have been | ||
+ | installing floorssince 1992 and have installed flooring and Tilling</div> | ||
+ | </div> | ||
+ | </li> | ||
+ | <!-- Slide 3 --> | ||
+ | <li data-description="Slide Description" data-easein="default" data-easeout="default" | ||
+ | data-fsmasterspeed="1500" data-fsslotamount="7" data-fstransition="fade" | ||
+ | data-hideafterloop="0" data-hideslideonmobile="off" data-index="rs-1683" | ||
+ | data-masterspeed="default" data-param1="" data-param10="" data-param2="" data-param3="" | ||
+ | data-param4="" data-param5="" data-param6="" data-param7="" data-param8="" data-param9="" | ||
+ | data-rotate="0" data-saveperformance="off" data-slotamount="default" | ||
+ | data-thumb="https://static.igem.org/mediawiki/2021/c/c1/T--CKWA-China--slide2.jpg" data-title="Slide Title" | ||
+ | data-transition="parallaxvertical"> | ||
+ | <img alt="" class="rev-slidebg" data-bgfit="cover" data-bgparallax="10" | ||
+ | data-bgposition="center center" data-bgrepeat="no-repeat" data-no-retina="" | ||
+ | src="https://static.igem.org/mediawiki/2021/c/c1/T--CKWA-China--slide3.jpg"> | ||
− | <div class=" | + | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" |
− | + | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | |
− | + | data-type="text" data-height="none" data-width="['700','700','700','700']" | |
− | + | data-whitespace="normal" data-hoffset="['15','15','15','15']" | |
+ | data-voffset="['-150','-150','-120','-120']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <h4>We Proudly Service</h4> | ||
+ | </div> | ||
− | </div> | + | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" |
+ | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | ||
+ | data-type="text" data-height="none" data-width="['1000','700','700','700']" | ||
+ | data-whitespace="normal" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['-60','-60','-60','-60']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <h2>These Metro Markets</h2> | ||
+ | </div> | ||
+ | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" | ||
+ | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | ||
+ | data-type="text" data-height="none" data-whitespace="normal" | ||
+ | data-width="['700','700','550','550']" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['30','40','0','30']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[-100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <div class="text">Flooring is a family-owned and operated business. we have been | ||
+ | installing floorssince 1992 and have installed flooring and Tilling</div> | ||
+ | </div> | ||
+ | </li> | ||
+ | <!-- Slide 4 --> | ||
+ | <li data-description="Slide Description" data-easein="default" data-easeout="default" | ||
+ | data-fsmasterspeed="1500" data-fsslotamount="7" data-fstransition="fade" | ||
+ | data-hideafterloop="0" data-hideslideonmobile="off" data-index="rs-1684" | ||
+ | data-masterspeed="default" data-param1="" data-param10="" data-param2="" data-param3="" | ||
+ | data-param4="" data-param5="" data-param6="" data-param7="" data-param8="" data-param9="" | ||
+ | data-rotate="0" data-saveperformance="off" data-slotamount="default" | ||
+ | data-thumb="https://static.igem.org/mediawiki/2021/c/c1/T--CKWA-China--slide3.jpg" data-title="Slide Title" | ||
+ | data-transition="parallaxvertical"> | ||
+ | <img alt="" class="rev-slidebg" data-bgfit="cover" data-bgparallax="10" | ||
+ | data-bgposition="center center" data-bgrepeat="no-repeat" data-no-retina="" | ||
+ | src="https://static.igem.org/mediawiki/2021/c/c1/T--CKWA-China--slide3.jpg"> | ||
− | <div class=" | + | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" |
+ | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | ||
+ | data-type="text" data-height="none" data-width="['700','700','700','700']" | ||
+ | data-whitespace="normal" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['-150','-150','-120','-120']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <h4>We Proudly Service</h4> | ||
+ | </div> | ||
+ | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" | ||
+ | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | ||
+ | data-type="text" data-height="none" data-width="['1000','700','700','700']" | ||
+ | data-whitespace="normal" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['-60','-60','-60','-60']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <h2>These Metro Markets</h2> | ||
+ | </div> | ||
+ | <div class="tp-caption" data-paddingbottom="[0,0,0,0]" data-paddingleft="[0,0,0,0]" | ||
+ | data-paddingright="[0,0,0,0]" data-paddingtop="[0,0,0,0]" data-responsive_offset="on" | ||
+ | data-type="text" data-height="none" data-whitespace="normal" | ||
+ | data-width="['700','700','550','550']" data-hoffset="['15','15','15','15']" | ||
+ | data-voffset="['30','40','0','30']" data-x="['left','left','left','left']" | ||
+ | data-y="['middle','middle','middle','middle']" | ||
+ | data-frames='[{"from":"y:[-100%];z:0;rX:0deg;rY:0;rZ:0;sX:1;sY:1;skX:0;skY:0;","mask":"x:0px;y:0px;s:inherit;e:inherit;","speed":1500,"to":"o:1;","delay":1000,"ease":"Power3.easeInOut"},{"delay":"wait","speed":1000,"to":"auto:auto;","mask":"x:0;y:0;s:inherit;e:inherit;","ease":"Power3.easeInOut"}]'> | ||
+ | <div class="text">Flooring is a family-owned and operated business. we have been | ||
+ | installing floorssince 1992 and have installed flooring and Tilling</div> | ||
+ | </div> | ||
+ | </li> | ||
− | <div | + | </ul> |
+ | </div> | ||
+ | </div> | ||
+ | </section> | ||
+ | <!--End Main Slider--> | ||
− | < | + | <!-- Service Detail Section --> |
− | + | <div class="service-detail-section"> | |
− | + | <div class="auto-container"> | |
− | + | <div class="sec-title text-center"> | |
− | + | <span class="title">Sureloc</span> | |
− | + | <h2>Surely Locate Cancer</h2> | |
− | <div class=" | + | </div> |
− | + | <div class="row clearfix padding-b"> | |
− | + | <div class="inner-box"> | |
− | + | <p class="text" style="text-indent:2em;"> | |
− | + | Non-small cell lung carcinoma (NSCLC) is a common type of epithelial cancer, which is not | |
− | + | sensitive to chemotherapy or radiotherapy. To address this issue, our team developed a | |
− | + | therapy based on magneto-hyperthermia. We designed a vector that codes for magnetic protein | |
− | + | crystals (MPCs) through the use of a tumor-specific promoter. Liposomes with surface | |
− | <div class=" | + | PEG-GE11 modifications carrying MPC vectors will target NSCLC cells. Post transfection, |
− | + | targeted tumor cells will express MPCs, which enable the binding of iron. Iron-loaded MPCs | |
− | + | will then respond to localized alternating magnetic fields and induce cell death. The active | |
− | + | targeting ligand, tumor-specific promoter, and localized alternating magnetic fields provide | |
− | + | triple targeting security. Currently, we completed the in vitro isolation and purification | |
− | + | of the MPCs with successful confirmation of their magnetism. The successive steps are to | |
− | + | control the MPCs’ size, add the internal targeting ligand, and experiment the targeting | |
− | + | capabilities in vivo. | |
− | <div class=" | + | </p> |
− | < | + | </div> |
− | + | </div> | |
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− | </ | + | |
− | </div> | + | |
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− | </ | + | |
− | </div> | + | |
− | </div> | + | |
+ | <div class="sec-title text-center"> | ||
+ | <span class="title">Our Video</span> | ||
+ | <h2>Promotional Video</h2> | ||
+ | </div> | ||
+ | <div class="row clearfix"> | ||
+ | <!-- News Block --> | ||
+ | <div class="news-block col-md-4 col-sm-6 col-xs-12"> | ||
+ | <div class="inner-box"> | ||
+ | <div class="image-box"> | ||
+ | <video class="gl_video" id="gl_video_2" src="video/mda-kc21c5bv2fig3ieu.mp4" | ||
+ | controls="“ture”"></video> | ||
+ | </div> | ||
+ | <div class="content-box"> | ||
+ | <h3>Here's the subject of the video</h3> | ||
+ | <div class="text">I could write some video notes here, a little bit more introduction. | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | <!-- News Block --> | ||
+ | <div class="news-block col-md-4 col-sm-6 col-xs-12"> | ||
+ | <div class="inner-box"> | ||
+ | <div class="image-box"> | ||
+ | <video class="gl_video" id="gl_video_2" src="video/mda-kc21c5bv2fig3ieu.mp4" | ||
+ | controls="“ture”"></video> | ||
+ | </div> | ||
+ | <div class="content-box"> | ||
+ | <h3>Here's the subject of the video</h3> | ||
+ | <div class="text">I could write some video notes here, a little bit more introduction. | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | <!-- News Block --> | ||
+ | <div class="news-block col-md-4 col-sm-6 col-xs-12"> | ||
+ | <div class="inner-box"> | ||
+ | <div class="image-box"> | ||
+ | <video class="gl_video" id="gl_video_2" src="video/mda-kc21c5bv2fig3ieu.mp4" | ||
+ | controls="“ture”"></video> | ||
+ | </div> | ||
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+ | <h3>Here's the subject of the video</h3> | ||
+ | <div class="text">I could write some video notes here, a little bit more introduction. | ||
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Revision as of 00:13, 28 September 2021
Surely Locate Cancer
Non-small cell lung carcinoma (NSCLC) is a common type of epithelial cancer, which is not sensitive to chemotherapy or radiotherapy. To address this issue, our team developed a therapy based on magneto-hyperthermia. We designed a vector that codes for magnetic protein crystals (MPCs) through the use of a tumor-specific promoter. Liposomes with surface PEG-GE11 modifications carrying MPC vectors will target NSCLC cells. Post transfection, targeted tumor cells will express MPCs, which enable the binding of iron. Iron-loaded MPCs will then respond to localized alternating magnetic fields and induce cell death. The active targeting ligand, tumor-specific promoter, and localized alternating magnetic fields provide triple targeting security. Currently, we completed the in vitro isolation and purification of the MPCs with successful confirmation of their magnetism. The successive steps are to control the MPCs’ size, add the internal targeting ligand, and experiment the targeting capabilities in vivo.