Team:KCIS NewTaipei

KCIS Home Page

Heart and Vitamin D
In the history of mankind, vitamin D
has always served a crucial role
in the maintenance of human health.

Besides regulating calcium homeostasis
and strengthening the immune system
,
it also has potential in
preventing COVID-19 infections.
The Problem
Vitamin D deficiency, a global pandemic caused largely by the lack of sunlight exposure, exacerbated during COVID-19 lockdowns.

However, all current solutions to vitamin D deficiency present limitations in efficiency or accessibility.

Due to these limitations, we came up with an innovative idea that presents a new method for vitamin D activation .
Man in the Dark
Plasmid Transformation Butyrate Production
Theory
By manipulating the acetyl-CoA
butyrate producing pathway, we can
increase the butyrate-producing
ability of probiotics.


The increased production of butyrate
would upregulate vitamin D receptor
expression
by increasing the activity
of the TGFβ pathway, which would
ultimately result in a more
efficient activation of vitamin D.

By introducing our engineered
fermented food starters,
we believe the project could
be implemented into daily diets,
opening up more opportunities
for a more efficient way
of vitamin D intake in the future.
+50%
total population are
vitamin D insufficient
in 2020 (global)
data circle
+1 Billion
cases are vitamin D
deficient in 2020
(global)
data circle

Follow Us:
Contact Us: